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Metreleptin
go.drugbank.com/drugs/DB09046ApprovedInvestigationalMetreleptin, a recombinant analog of the human hormone leptin, is an orphan drug used to treat complications of leptin deficiency in people with lipodystrophy. … Metreleptin is produced in _E. coli_ and differs from native human leptin by the addition of a methionine residue at its amino terminus.
Potassium acetate
go.drugbank.com/drugs/DB14498ApprovedMixtures: NUTRIFLEX LIPID PERI INFUZYONLUK IV EMULSIYON, 2500 ML, NUTRIFLEX LIPID PERI INFUZYONLUK IV EMULSIYON, 1250 MLZinc acetate
go.drugbank.com/drugs/DB14487ApprovedInvestigationalMixtures: NUTRIFLEX LIPID PERI INFUZYONLUK IV EMULSIYON, 2500 ML, NUTRIFLEX LIPID PERI INFUZYONLUK IV EMULSIYON, 1250 MLPork collagen
go.drugbank.com/drugs/DB14100ApprovedIt serves as an alternative repair treatment for patients with inadequate response to pre-existing surgical methods. … Pork Collagen is used within MACI® (autologous cultured chondrocytes on porcine collagen membrane) as an autologous cellularized scaffold product indicated for the repair of single or multiple symptomatic
Mixtures: P3 Rg, P3 RgNicoboxil
go.drugbank.com/drugs/DB12911ApprovedWithdrawnNevertheless, it is predominantly found paired with nonivamide as a combination topical analgesic product where its proposed mechanism of action as a rubefacient is complementary and ultimately synergistic … Nicoboxil has been investigated for the treatment of Acute Low Back Pain, where it is typically considered an effective and safe therapeutic option.
PF-5212372
go.drugbank.com/drugs/DB19212InvestigationalPF-5212372 is under investigation in clinical trial NCT02795832 (A Study to Determine the Safety & Efficacy of ZPL-5212372 in Healthy Subjects and in Subjects With Atopic Dermatitis).
Categories: Phospholipase A2 InhibitorsDipyridamole
go.drugbank.com/drugs/DB00975ApprovedInvestigationalA phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesTirzepatide
go.drugbank.com/drugs/DB15171ApprovedInvestigational[A246260] Tirzepatide comprises a 39 amino acid linear synthetic peptide conjugated to a C20 fatty diacid moiety. … Dual GIP/GLP-1 agonists gained increasing attention as new therapeutic agents for glycemic and weight control as they demonstrated better glucose control and weight loss compared to selective GLP-1 receptor
Phenobarbital
go.drugbank.com/drugs/DB01174ApprovedInvestigationalA barbituric acid derivative that acts as a nonselective central nervous system depressant.
Mixtures: PB Hyos, Re-PB HyosCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic IndexPH-797804
go.drugbank.com/drugs/DB07941InvestigationalPH-797804 has been investigated for the treatment of Osteoarthritis.