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Displaying results 1061 - 1070 of 2420 in total
  1. Drug

    Mobocertinib

    go.drugbank.com/drugs/DB16390
    ApprovedInvestigationalWithdrawn

    Mobocertinib is a kinase inhibitor targeted against human epidermal growth factor receptor (EGFR). It is used specifically in the treatment of non-small cell lung cancer (NSCLC) caused by exon 20 insertion mutations in the EGFR gene, whi...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  2. Drug

    Azvudine

    go.drugbank.com/drugs/DB16407
    Investigational

    Azvudine is under investigation in clinical trial NCT04668235 (Study on Safety and Clinical Efficacy of AZVUDINE in COVID-19 Patients (Sars-cov-2 Infected)).

  3. Drug

    Goldenseal

    go.drugbank.com/drugs/DB16594
    Approved

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C19 Inhibitors
  4. Drug

    Repotrectinib

    go.drugbank.com/drugs/DB16826
    ApprovedInvestigational

    Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene. ROS1 mutations are one...

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP2C19 Inducers
  5. Drug

    Azasetron

    go.drugbank.com/drugs/DB16837
    Investigational

    Categories: P-glycoprotein substrates
  6. Drug

    Rhodamine B

    go.drugbank.com/drugs/DB16853
    Experimental

    Categories: P-glycoprotein substrates
  7. Drug

    Naringin

    go.drugbank.com/drugs/DB16859
    Experimental

    Categories: Cytochrome P-450 CYP3A Inhibitors, P-glycoprotein inhibitors
  8. Drug

    Tanshinone I

    go.drugbank.com/drugs/DB16886
    Experimental

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 Inhibitors
  9. Drug

    BPR-0L075

    go.drugbank.com/drugs/DB17155
    Investigational

    Categories: Cytochrome P-450 CYP1A2 Substrates, Cytochrome P-450 Substrates
  10. Drug

    EP-0042

    go.drugbank.com/drugs/DB18120
    Investigational

    Categories: Cytochrome P-450 CYP3A Substrates, Cytochrome P-450 Substrates