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Displaying results 1061 - 1070 of 10000 in total
  1. Drug

    Guanosine tetraphosphate

    go.drugbank.com/drugs/DB04022
    Experimental

    Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. … Guanosine tetraphosphate is a guanine nucleotide containing four phosphate groups.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: Guanosine-5',3'-tetraphosphate
  2. Drug

    Lenacapavir

    go.drugbank.com/drugs/DB15673
    ApprovedInvestigational

    [A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy _in vitro_, little to no cross-resistance with existing antiretroviral … [L42995] On December 22, 2022, it was also approved by the FDA.[L44473]

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: -3-(TRIFLUOROMETHYL)-3B,4,4A,5-TETRAHYDRO-1H-CYCLOPR, DIFLUOROPHENYL)ETHYL)-5,5-DIFLUORO-3B,4,4A,5-TETRAHYD
  3. Drug

    Dasatinib

    go.drugbank.com/drugs/DB01254
    ApprovedInvestigational

    [A11377,A33432] Dasatinib also inhibits a spectrum of kinases involved in cancer, including several SRC-family kinases. … BCR-ABL is associated with the uncontrolled activity of the ABL tyrosine kinase and is involved in the pathogenesis of CML and 15-30% of ALL cases.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide
  4. Drug

    CRA_16847

    go.drugbank.com/drugs/DB02063
    Experimental

    Synonyms: 2-(3-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}-5-BROMO-4-OXIDOPHENYL)SUCCINATE
  5. Drug

    Cinoxacin

    go.drugbank.com/drugs/DB00827
    ApprovedWithdrawn

    Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.

    Categories: Heterocyclic Compounds, 3-Ring, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acid, 1-ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid
  6. Drug

    Betazole

    go.drugbank.com/drugs/DB00272
    Approved

    A histamine H2 agonist used clinically to test gastric secretory function.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-(1H-pyrazol-5-yl)ethanamine, 2-(3-pyrazolyl)ethylamine
  7. Drug

    (Rp)-cAMPS

    go.drugbank.com/drugs/DB01790
    Experimental

    Synonyms: (Rp)-adenosine-3',5'-cyclic monophosphorothioate, adenosine-3',5'-cyclic monophosphorothioate, Rp-isomerCategories: Heterocyclic Compounds, 2-Ring
  8. Drug

    SLC-391

    go.drugbank.com/drugs/DB18814
    Investigational

    Synonyms: 2-Pyridinamine, 3-[5-(cyclopropylmethyl)-1,3,4-oxadiazol-2-yl]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-
  9. Drug

    North-methanocarbathymidine

    go.drugbank.com/drugs/DB17805
    Investigational

    Synonyms: N-methanocarbathymidine, 2,4(1h,3h)-pyrimidinedione, 1-(4-hydroxy-5-(hydroxymethyl)bicyclo(3.1.0)hex-2-yl)-5-methyl-, (1s-(1.alpha.,2.alpha.,4.beta.,5.alpha.))-Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Ginsenoside Rd

    go.drugbank.com/drugs/DB19256
    Investigational

    Ginsenoside Rd is under investigation in clinical trial NCT00815763 (Efficacy and Safety of Ginsenoside-rd for Acute Ischemic Stroke).

    Synonyms: -d-glucopyranoside, (3.beta.,12.beta.)-20-(.beta.-d-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-o-.beta.-d-glucopyranosyl-