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Bimiralisib
go.drugbank.com/drugs/DB14846InvestigationalBimiralisib is under investigation in clinical trial NCT02723877 (PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)).
Synonyms: 2-Pyridinamine, 5-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)-, 5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amineArginine glutamate
go.drugbank.com/drugs/DB13207InvestigationalSynonyms: (2S)-2-amino-5-guanidino-pentanoic acid;(2S)-2-aminopentanedioic acid, L-Arginine L-glutamateCaptopril
go.drugbank.com/drugs/DB01197ApprovedInvestigationalATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension. … Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).
Mixtures: CAPOZIDE 50/25 MG TABLETAS, CAPTOPRIL E IDROCLOROTIAZIDE HEXALCategories: P-glycoprotein inhibitorsEthyl (4R)-4-{[(2R,5S)-2-(4-fluorobenzyl)-6-methyl-5-{[(5-methyl-1,2-oxazol-3-yl)carbonyl]amino}-4-oxoheptanoyl]amino}-5-[(3S)-2-oxo-3-pyrrolidinyl]pentanoate
go.drugbank.com/drugs/DB02313ExperimentalSynonyms: Ethyl (4R)-4-{[(2R,5S)-2-(4-fluorobenzyl)-6-methyl-5-{[(5-methyl-1,2-oxazol-3-yl)carbonyl]amino}-4-oxoheptanoyl]amino}-5-[(3S)-2-oxo-3-pyrrolidinyl]pentanoatePropylthiouracil
go.drugbank.com/drugs/DB00550ApprovedA thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-Mercapto-6-propyl-4-pyrimidone, 2-Mercapto-6-propylpyrimid-4-oneCP-526423
go.drugbank.com/drugs/DB02089ExperimentalSynonyms: 1,2-bis(2-(5-chloroindole-2-carbonylamino)ethoxy)ethane, bis[5-chloro-1h-indol-2-yl-carbonyl-aminoethyl]-ethylene glycolCategories: Heterocyclic Compounds, 2-RingFentiazac
go.drugbank.com/drugs/DB13217ExperimentalCategories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingSynonyms: 4-(4-Chlorophenyl)-2-phenyl-5-thiazoleacetic acid, 4-(p-Chlorophenyl)-2-phenyl-5-thiazoleacetic acid(2S)-1-{[5-(1H-Indazol-5-yl)-3-pyridinyl]oxy}-3-(7aH-indol-3-yl)-2-propanamine
go.drugbank.com/drugs/DB06977ExperimentalSynonyms: (2S)-1-{[5-(1H-Indazol-5-yl)-3-pyridinyl]oxy}-3-(7aH-indol-3-yl)-2-propanamineSunvozertinib
go.drugbank.com/drugs/DB18925Investigational[A274143] Sunvozertinib was granted accelerated approval in the US on July 2, 2025 for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor … [L53488] EGFR is a transmembrane protein with cytoplasmic kinase activity commonly expressed by non-small cell lung carcinomas (NSCLCs).
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 2-Propenamide, N-[5-[[4-[[5-chloro-4-fluoro-2-(1-hydroxy-1- methylethyl)phenyl]amino]-2-pyrimidinyl]amino]-2-[(3R)-3-(dimethylamino)-1-pyrrolidinyl]-4-methoxyphenyl]-, N-{5-[(4-{[5-chloro-4-fluoro-2-(1-hydroxy-1-methylethyl)phenyl]amino}pyrimidin-2-yl)amino]-2-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl}prop-2-enamideL-Pentahomoserine
go.drugbank.com/drugs/DB03105ExperimentalSynonyms: 5-Hydroxy-2-aminovaleric acid, L-5-Hydroxynorvaline