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Azercabtagene zapreleucel
go.drugbank.com/drugs/DB17185InvestigationalSynonyms: Adult allogeneic CD4+ and CD8+ enriched T cells transduced with an anti-CD19 chimeric antigen receptor (CAR) that is site-specific integrated into the cellular genome., Adult allogeneic CD4+ and CD8+ enriched T cells, gene edited through the electroporatiErgidina
go.drugbank.com/drugs/DB18565ExperimentalErgidina is a recombinant human minibody against complement component C5 fused with RGD-motif.
Synonyms: Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 and the cyclic RGD-4C peptide (ACDCRGDCFCG)NGN-401
go.drugbank.com/drugs/DB18594InvestigationalNGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding
Synonyms: Recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2NKX101
go.drugbank.com/drugs/DB18131InvestigationalNKX101 is an investigational allogeneic chimeric antigen receptor (CAR)-natural killer cell therapy.
Synonyms: a fourth generation activating chimeric receptor (ACR) natural killer (NK) cell therapy engineered with an NKG2D ACR, OX40 costimulatory domain, CD3zeta signaling moiety, and membrane bound IL-15 (mb-IL15AOC-1020
go.drugbank.com/drugs/DB18621InvestigationalAOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded
Synonyms: An antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotideTavokinogene telseplasmid
go.drugbank.com/drugs/DB17301InvestigationalTavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.
Synonyms: Dna plasmid containing genes coding for the human interleukin 12 (il-12) p35 and p40 subunits that are separated by an internal ribosomal entry site (ires) and under the control of a single cytomegalovirusLawsonia inermis leaf
go.drugbank.com/drugs/DB14313InvestigationalIt is not an approved drug.
Synonyms: Plants and Plant Parts, Henna Lawsonia InermisTifcemalimab
go.drugbank.com/drugs/DB18914InvestigationalTifcemalimab is under investigation in clinical trial NCT06095583 (Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)).
Synonyms: Immunoglobulin g4, anti-(human b and t lymphocyte attenuator (btla)) (human-mus musculus monoclonal js004 .gamma.4-chain), disulfide with human-mus musculus monoclonal js004 .kappa.-chain, dimerAD-214
go.drugbank.com/drugs/DB18412InvestigationalSynonyms: Fc-fusion protein comprised of an anti-CXCR4 i-body tethered at its C-terminus to constant domains 2 and 3 of the Fc region of a mutated human IgG1