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Displaying results 101 - 110 of 449 in total
  1. Drug

    Unasnemab

    go.drugbank.com/drugs/DB18837
    Investigational

    Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury).

    Synonyms: Immunoglobulin g1, anti-(human repulsive guidance molecule rgma) (human-mus musculus clone rh116a3 .gamma.1-chain), disulfide with human-mus musculus clone rh116a3 .kappa.-chain, dimer
  2. Drug

    Befovacimab

    go.drugbank.com/drugs/DB16188
    Investigational

    Synonyms: Immunoglobulin g2, anti-(human tissue factor pathway inhibitor) (human monoclonal 1093884 .gamma.2-chain), disulfide with human monoclonal 1093884 .lambda.-chain, dimer, Human tissue factor pathway inhibitor-neutralizing antibody (bay 1093884)
  3. Drug

    Zenocutuzumab

    go.drugbank.com/drugs/DB15559
    ApprovedInvestigational

    Zenocutuzumab is a low-fucose humanized full-length immunoglobulin G1 (IgG1) bispecific HER2- and HER3-directed bispecific antibody. … [L51963] It works to attenuate aberrant cancer cell growth caused by genomic rearrangements involving the neuregulin 1 gene (NRG1), which is an oncogenic driver.

    Categories: Immunoglobulins, Antibodies, Monoclonal, HumanizedSynonyms: Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized clone mcla-128 .gamma.1-chain), disulfide with humanized clone mcla-128 light chain, dimer
  4. Drug

    Galegenimab

    go.drugbank.com/drugs/DB18860
    Investigational

    Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to

    Synonyms: Immunoglobulin igg1 fab fragment, anti-(human serine proteinase htra1) (human-mus musculus monoclonal fhtr2163 .gamma.1-chain), disulfide with human-mus musculus monoclonal fhtr2163 .kappa.-chain
  5. Drug

    Divozilimab

    go.drugbank.com/drugs/DB18878
    Investigational

    Divozilimab is under investigation in clinical trial NCT05730699 (Efficacy and Safety of Divozilimab in Patients With Neuromyelitis Optica Spectrum Disorders (AQUARELLE)).

    Synonyms: Immunoglobulin g1, anti-(human cd20 antigen) (human-mus musculus monoclonal bcd-132 .gamma.1-chain), disulfide with human-mus musculus monoclonal bcd-132 .kappa.-chain, dimerCategories: Immunoglobulins
  6. Drug

    Ligufalimab

    go.drugbank.com/drugs/DB17542
    Investigational

    Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47. … It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With Myelodysplastic Syndrome).

    Synonyms: Immunoglobulin g4 (225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal ak117 .gamma.4-chain), disulfide with human-mus musculus monoclonal ak117 .kappa.-chain, dimer
  7. Drug

    Posdinemab

    go.drugbank.com/drugs/DB18941
    Investigational

    Posdinemab is under investigation in clinical trial NCT04619420 (A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease).

    Synonyms: Immunoglobulin G1, anti-(human phosphorylated tau protein) (human-Mus musculus monoclonal JNJ-63733657 γ1-chain), disulfide with human-Mus musculus monoclonal JNJ-63733657 κ-chain, dimer
  8. Drug

    Perenostobart

    go.drugbank.com/drugs/DB18602
    Investigational

    Perenostobart is an alpha-CD39 IgG4 monoclonal antibody.

    Synonyms: Immunoglobulin G4 [229-proline], anti-(human ectonucleoside triphosphate diphosphohydrolase 1) (human monoclonal SRF617 γ4-chain), disulfide with human monoclonal SRF617 κ-chain, dimer, immunoglobulin G4-kappa, anti-[ENTPD1(ectonucleoside triphosphate diphosphohydrolase 1, NTPDase-1, ATPDase, SPG64, CD39)], Homo sapiens monoclonal antibody
  9. Drug

    Atibuclimab

    go.drugbank.com/drugs/DB06546
    Investigational

    Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis.

    Categories: ImmunoglobulinsSynonyms: IMMUNOGLOBULIN G4, ANTI-(HUMAN CD14 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IC14 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL IC14 .KAPPA.-CHAIN, DIMER, IC14, (RECOMBINANT CHIMERIC MAB AGAINST HUMAN CD14)
  10. Drug

    Tilavonemab

    go.drugbank.com/drugs/DB17014
    Investigational

    Synonyms: Immunoglobulin g4, anti-(human tau protein) (human-mus musculus monoclonal pr-1649264 .gamma.4-chain), disulfide with human-mus musculus monoclonal pr-1649264 .kappa.-chain, dimerCategories: Immunoglobulins, Recombinant Humanized Anti-Tau Antibody