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Sabestomig
go.drugbank.com/drugs/DB19326InvestigationalSabestomig is under investigation in clinical trial NCT05216835 (Safety and Preliminary Efficacy Assessment of AZD7789 in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma).
Synonyms: 3, TIM3, TIM-3, TIMD3, CD366)], humanized and Ho, Immunoglobulin G1-kappa/lambda, anti-[Homo sapiens PDCD1 (programmed cell death 1, PD1, PD-1, CD279) and HAVCR2 (hepatitis A virus cellular receptor 2, T cell immunoglobulin and mucin domains family memberButylidenephthalide
go.drugbank.com/drugs/DB17259ExperimentalSynonyms: 3-butylidenephthalide, mixture of cis and trans isomers, N-butylidenephthalide, (e)+(z)Ociperlimab
go.drugbank.com/drugs/DB18947InvestigationalIII Unresectable Non-small Cell Lung Cancer). … Ociperlimab is under investigation in clinical trial NCT04866017 (A Study to Compare Ociperlimab Plus Tislelizumab Versus Durvalumab Following Concurrent Chemoradiotherapy (Ccrt) in Patients With Stage
Synonyms: Immunoglobulin g1-kappa, anti-(homo sapiens tigit (t-cell immunoreceptor with ig domain and itim, v-set ig member 9, vsig9, v-set and transmembrane member 3, vstm3)), humanized monoclonal antibody (ociperlimab(-)-menthol 1-propylene glycol carbonate
go.drugbank.com/drugs/DB14136InvestigationalSynonyms: Fema no. 3806, 1-propylene glycol carbonateMixtures: Thera Derm Roll OnZifibancimig
go.drugbank.com/drugs/DB19332InvestigationalZifibancimig is under investigation in clinical trial NCT04567303, focusing on participants with neovascular age-related macular degeneration.
Synonyms: Immunoglobulin G1 Fab fragment, bispecific, anti-(human vascular endothelial growth factor A and angiopoietin 2) (human monoclonal RO7250284 γ1-chain), disulfide with human monoclonal RO7250284 κ-chain, mmunoglobulin Fab G1-kappa, anti-[Homo sapiens ANGPT2 (angiopoietin 2, Ang2)] and anti-[Homo sapiens VEGFA (vascular endothelial growth factor A, VEGF-A, VEGF), monoclonal antibody, bispecific, biparatopeAzercabtagene zapreleucel
go.drugbank.com/drugs/DB17185InvestigationalSynonyms: Adult allogeneic CD4+ and CD8+ enriched T cells transduced with an anti-CD19 chimeric antigen receptor (CAR) that is site-specific integrated into the cellular genome., Adult allogeneic CD4+ and CD8+ enriched T cells, gene edited through the electroporatiErgidina
go.drugbank.com/drugs/DB18565ExperimentalErgidina is a recombinant human minibody against complement component C5 fused with RGD-motif.
Synonyms: Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 and the cyclic RGD-4C peptide (ACDCRGDCFCG)NGN-401
go.drugbank.com/drugs/DB18594InvestigationalDeveloped by Neurogene Inc., it is being investigated for the treatment of Rett syndrome. … NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding
Synonyms: Recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2NKX101
go.drugbank.com/drugs/DB18131InvestigationalNKX101 is an investigational allogeneic chimeric antigen receptor (CAR)-natural killer cell therapy.
Synonyms: a fourth generation activating chimeric receptor (ACR) natural killer (NK) cell therapy engineered with an NKG2D ACR, OX40 costimulatory domain, CD3zeta signaling moiety, and membrane bound IL-15 (mb-IL15Tavokinogene telseplasmid
go.drugbank.com/drugs/DB17301InvestigationalTavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.
Synonyms: Dna plasmid containing genes coding for the human interleukin 12 (il-12) p35 and p40 subunits that are separated by an internal ribosomal entry site (ires) and under the control of a single cytomegalovirus, Dna plasmid encoding interleukin-12 ino-9012