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Displaying results 101 - 110 of 303 in total
  1. Drug

    Briquilimab

    go.drugbank.com/drugs/DB18136
    Investigational

    Briquilimab is a humanized aglycosylated IgG1 kappa monoclonal antibody targeting CD117 (cKit).

    Synonyms: IMMUNOGLOBULIN G1 (297-GLUTAMINE), ANTI-(HUMAN C-KIT RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JSP191 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL JSP191 .KAPPA.-CHAIN, DIMER
  2. Drug

    RP-72

    go.drugbank.com/drugs/DB17156
    Investigational

    Synonyms: CXC chemokine receptor types 1 and 2 inhibitor RP72
  3. Drug

    Telitacicept

    go.drugbank.com/drugs/DB18312
    Investigational

    Synonyms: 13-118-tumor necrosis factor receptor superfamily protein tnfrsf13b (human extracellular domain fragment) fusion protein with immunoglobulin g1, (human rc18 fc fragment), dimer, (L120>A,L121>E,G123>A,A216>S,P217>S)-TACI (TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR, TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY PROTEIN TNFRSF13B) HUMAN EXTRACELLULAR DOMAIN FRAGMENT (13-118)-PEPTIDE
  4. Drug

    Vixarelimab

    go.drugbank.com/drugs/DB16350
    Investigational

    Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Prurigo Nodularis).

    Synonyms: Immunoglobulin g (234-proline,303-glutamine), anti-(human oncostatin m receptor subunit .beta.) (human monoclonal kpl-716 .gamma.-chain), disulfide with human monoclonal kpl-716 .lambda.-chain, dimer
  5. Drug

    Stapokibart

    go.drugbank.com/drugs/DB18990
    Investigational

    Stapokibart is under investigation in clinical trial NCT06424470 (Study on the Treatment of Prurigo Nodularis With Stapokibart Injection).

    Synonyms: Immunoglobulin G4 [227-proline], anti-(human interleukin 4 receptor subunit α) (human-Mus musculus monoclonal CM310 γ4-chain), disulfide with human-Mus musculus monoclonal CM310 κ-chain, dimer
  6. Drug

    Domvanalimab

    go.drugbank.com/drugs/DB18848
    Investigational

    Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-small Cell Lung Cancer).

    Synonyms: Immunoglobulin g1 (236-alanine,237-alanine,de-c-terminal-lysine), anti-(human receptor tigit)(human-mus musculus monoclonal ab154 .gamma.1-chain), disulfide with human-mus musculus monoclonal ab154 .kappa
  7. Drug

    NKX101

    go.drugbank.com/drugs/DB18131
    Investigational

    NKX101 is an investigational allogeneic chimeric antigen receptor (CAR)-natural killer cell therapy.

    Synonyms: a fourth generation activating chimeric receptor (ACR) natural killer (NK) cell therapy engineered with an NKG2D ACR, OX40 costimulatory domain, CD3zeta signaling moiety, and membrane bound IL-15 (mb-IL15
  8. Drug

    Enapotamab vedotin

    go.drugbank.com/drugs/DB16156
    Investigational

    Enapotamab vedotin is under investigation in clinical trial NCT02988817 (Enapotamab Vedotin (Humax-axl-adc) Safety Study in Patients With Solid Tumors).

    Synonyms: Immunoglobulin g1, anti-(human growth factor receptor axl)(human humax-axl .gamma.1-chain), disulfide with human humax-axl .kappa.-chain, dimer tetrakis(thioether) with vedotin
  9. Drug

    AOC 1001

    go.drugbank.com/drugs/DB18620
    Investigational

    Delpacibart (AOC 1001) is being investigated in a global study for the treatment of Myotonic Dystrophy type 1 (DM1) in clinical trial NCT06411288

    Synonyms: Immunoglobulin G1 [233-alanine,234-alanine,327-arginine,de-446-lysine], anti-(human type 1 transferrin receptor) (human-Mus musculus clone AV05 γ1-chain), disulfide with human-Mus musculus clone AV05 κ-chain
  10. Drug

    Zilovertamab

    go.drugbank.com/drugs/DB18403
    Investigational

    Synonyms: Immunoglobulin g1, anti-(human receptor tyrosine kinase ror-1) (human-mus musculus monoclonal uc-961 .gamma.1-chain), disulfide with human-mus musculus monoclonal uc-961 .kappa.-chain, dimer