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3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL
go.drugbank.com/drugs/DB07712ExperimentalSynonyms: 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OLZavegepant
go.drugbank.com/drugs/DB15688ApprovedInvestigationalof oral zavegepant (150 mg bid) in subjects with mild allergic asthma. … [L45505] CGRP is released from sensory nerves and acts as a strong vasodilator, and thanks to these properties, it is involved in pain pathways.
Categories: MATE 1 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 1-piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-n-((1r)-1-((7-methyl-1h-indazol-5-yl)methyl)-2-(4-(1-methyl-4-piperidinyl)-1-piperazinyl)-2-oxoethyl)-Mupirocin
go.drugbank.com/drugs/DB00410ApprovedInvestigationalVet approvedMupirocin, formerly termed pseudomonic acid A,[A178531] is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents. … Produced by fermentation using the organism _Pseudomonas fluorescens_, mupirocin is a naturally-occurring antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain
Synonyms: 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3- [(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl] oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid, Pseudomonic acid AInternational brands: T-Bact5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamide
go.drugbank.com/drugs/DB07180ExperimentalSynonyms: 5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamideN-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE
go.drugbank.com/drugs/DB07630ExperimentalSynonyms: N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDEGuanosine tetraphosphate
go.drugbank.com/drugs/DB04022ExperimentalTwo phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. … Guanosine tetraphosphate is a guanine nucleotide containing four phosphate groups.
Categories: Heterocyclic Compounds, 2-Ring, Nucleic Acids, Nucleotides, and NucleosidesSynonyms: Guanosine-5',3'-tetraphosphate4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol
go.drugbank.com/drugs/DB03687ExperimentalSynonyms: 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol, 4-CDP-2-C-methyl-D-erythritol5-(2-Fluoro-5-{(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]-1-propen-1-yl}phenyl)-1,2-oxazole-3-carboxylic acid
go.drugbank.com/drugs/DB02014ExperimentalSynonyms: 5-{2-fluoro-5-[3-(3-hydroxy-2-methoxycarbonyl-phenoxy)-propenyl]-phenyl}-isoxazole-3-carboxylic acidCinoxacin
go.drugbank.com/drugs/DB00827ApprovedWithdrawnSynthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Categories: Heterocyclic Compounds, 3-Ring, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: 1-ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid, 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acidIxazomib
go.drugbank.com/drugs/DB09570ApprovedInvestigational[A264319] It was later approved by Health Canada on August 3, 2016,[L51239] and by the EMA on November 21, 2016. … [A7948] More than 99% of the drug compound is the R-enantiomer.[A264329] Ixazomib was approved by the FDA on November 20, 2015, making it the first oral proteasome inhibitor approved in the US.
Categories: Antineoplastic and Immunomodulating Agents, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: 2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-5-oxo-1,3,2-dioxaborolane-4,4-diacetic acid, ((1R)-1-((2,5-DICHLOROBENZAMIDO)ACETAMIDO)-3-METHYLBUTYL)BORONIC ACID