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Gefitinib
go.drugbank.com/drugs/DB00317ApprovedInvestigationalIt is marketed by AstraZeneca under the trade name Iressa.
Synonyms: 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamineProducts: GEFITINIB EG, İRESSA 250 MG FİLM KAPLI TABLET, 30 ADETSodium aurothiomalate
go.drugbank.com/drugs/DB09276ApprovedWithdrawnGold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL. … It is most effective in active progressive rheumatoid arthritis and of little or no value in the presence of extensive deformities or in the treatment of other forms of arthritis.
Products: MYOCRISIN INJECTION 20 MG (4% W/V), MIOCRIN 50 MGDigitoxin
go.drugbank.com/drugs/DB01396ApprovedWithdrawnIt has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)
Products: Digimerck 0,1 mg/ml - Injektionslösung, Digimerck 0,07 mg - TablettenSimeprevir
go.drugbank.com/drugs/DB06290ApprovedWithdrawnSustained virologic response 12 weeks after planned end of treatment (SVR12) was achieved in 170/176 (97%) subjects without cirrhosis treated with 12 weeks simeprevir in combination with sofosbuvir (FDA … The overall SVR12 was 88% (44/50) in treatment-naïve patients with cirrhosis [L852].
Products: OLYSIO 150 MG KAPSUL ,KAPSUL, 28 ADETTenapanor
go.drugbank.com/drugs/DB11761ApprovedInvestigational[L8558] It was first designed and synthesized in 2012. … [A185492] As an inhibitor of the sodium/hydrogen exchanger isoform 3 (NHE3) transporter, it is the first and currently only medication within its class[A185489,A185492,A185495] and therefore exists as
Products: XPHOZAH 10 mg, XPHOZAH 20 mgRoflumilast
go.drugbank.com/drugs/DB01656ApprovedInvestigational[L46546] It was first approved by the EMA in July 2010, and by the FDA in January 2018.[L37564] Roflumilast topical cream is indicated to treat plaque psoriasis. … [A251385] The resultant increase in intracellular cAMP induced by roflumilast's inhibition of PDE4 is thought to mediate its disease-modifying effects, although its precise mechanism of action has yet
Products: ROFLUNG 0,5 MG SAŞE ,30 SAŞE, ROFLUNG 0,5 MG SAŞE ,90 SAŞEHeparin
go.drugbank.com/drugs/DB01109ApprovedInvestigationalIt is a naturally occurring anticoagulant released from mast cells. … It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa.
Mixtures: NOSKAR 100 MG/50 IU/10 MG / G, JEL 120 G, NOSKAR 100 MG/50 IU/10 MG / G, JEL 50 GProducts: Hepalean-lok 10 USP, HEPARINUM 25.000 IU/5 ML IV ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON, 10 FLAKONNortriptyline
go.drugbank.com/drugs/DB00540ApprovedInvestigational[L11878] It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.[L11881]
Products: APO-NORTRIPTYLINE CAPSULE 10 mg, APO-NORTRIPTYLINE CAPSULE 25 mgMigalastat
go.drugbank.com/drugs/DB05018ApprovedInvestigational[L47036,L47057,L4274,L4278] Globally, it is estimated that approximately 35 to 50 percent of Fabry patients may have amenable GLA variants that are treatable with migalastat. … [L47036,L47057,L4274,L4278] In the U.S., it is estimated that more than 3,000 people are living with Fabry disease, and an estimated more than 50 percent of these diagnosed patients are currently untreated
Products: GALAFOLD 123 MG SERT KAPSÜL, 14 ADETExemestane
go.drugbank.com/drugs/DB00990ApprovedInvestigationalIt irreversibly binds to the active site of the enzyme resulting in permanent inhibition.
Synonyms: 6-methyleneandrosta-1,4-diene-3,17-dioneProducts: EXEMESTANE EG, AROMASIN 25 MG DRAJE, 30 ADET