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Evening primrose oil
go.drugbank.com/drugs/DB11358ApprovedNutraceutical[A33131] Evening primrose oil has been filled for the FDA by Humanetics Corporation on April 2000 to be a new dietary ingredient but its current status is "Inadequate basis for expectation of safety". … In its composition it presents some fatty acids such as [DB00132] and [DB13854].
Products: Nn EVENING PRIMROSE OIL 1000MG (with 10%GLA), Nn EVENING PRIMROSE OIL 500MG (with 10% GLA)Gadofosveset trisodium
go.drugbank.com/drugs/DB06705ApprovedIn this way, gadofosveset trisodium is used to help diagnose certain disorders of the heart and blood vessels. … Gadofosveset trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA), which is a non-invasive way of imaging blood vessels.
Categories: Diagnostic Uses of Chemicals, Compounds used in a research, industrial, or household settingCasimersen
go.drugbank.com/drugs/DB14984ApprovedInvestigationalon further verification in confirmatory trials. … Casimersen was granted accelerated FDA approval on February 25, 2021, based on data showing an increase in dystrophin levels in skeletal muscle of patients treated with casimersen; this approval is contingent
Categories: Compounds used in a research, industrial, or household settingEstradiol valerate
go.drugbank.com/drugs/DB13956ApprovedInvestigationalVet approveddue to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure, and for the treatment of advanced androgen-dependent carcinoma of the prostate (for palliation … The primary source of estrogen in normally cycling adult women is the ovarian follicle, which secretes 70 to 500 mcg of estradiol daily, depending on the phase of the menstrual cycle.
Mixtures: CYCLO PROGYNOVA N 2MG/0.15, CYCLO PROGYNOVA N 2MG/0.15Aprotinin
go.drugbank.com/drugs/DB06692ApprovedInvestigationalWithdrawnThe goal of using of aprotinin was subsequently to minimize end-organ damage resulting from hypotension due to blood loss in surgery and to reduce the necessity for blood transfusions during surgery. … Nevertheless, the drug was formally withdrawn worldwide in May of 2008 after studies confirmed that its use enhanced the risk of complications or death.
Mixtures: SAN. VE TİC. LTD., TISSEEL FIBRIN SEALANT VH S/D (FROZEN)Bromothalonil
go.drugbank.com/drugs/DB14199ApprovedIt is also a known allergen and dermatological irritant that has been banned in many EU countries due to increasing rates of contact allergy [A34322]. … In 2005, MDBGN was named in the top 15 most frequently positive allergens identified in patch tests by the North American Contact Dermatitis Group (NACDG)[A34326].
Categories: Compounds used in a research, industrial, or household settingSaccharomyces cerevisiae
go.drugbank.com/drugs/DB10447ApprovedSaccharomyces cerevisiae is used in allergenic testing.
Mixtures: P3 Oa, P3 OaCategories: Non-Standardized Food Allergenic Extract, Non-Standardized Fungal Allergenic ExtractPodophyllin
go.drugbank.com/drugs/DB09094ApprovedPodophyllin is a resin extracted from the roots of _Podophyllum peltatum_ (American mandrake) and _Podophyllum emodi_, which contains numerous compounds, amongst which is podophyllin (as well as the drug … Podophyllin arrests mitosis in metaphase.
Mixtures: Verban OntCategories: Compounds used in a research, industrial, or household settingChlorthalidone
go.drugbank.com/drugs/DB00310ApprovedInvestigationalChlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. … be partly the result of reductions in carbonic anhydrase–dependent pathways.
Categories: combinations of sulfonamides, Non Potassium Sparing DiureticsMethadone
go.drugbank.com/drugs/DB00333ApprovedInvestigational(due to a lack of active metabolites), minimal accumulation in renal failure, good bioavailability, low cost, and a long duration of action. … [A185888,A185891,A185897] Compared with [morphine], the gold standard reference opioid, methadone also acts as an agonist of κ- and σ-opioid receptors, as an antagonist of the N-methyl-D-aspartate (NMDA
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Drugs Used in Opioid DependenceSynonyms: dl-Methadone