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Displaying results 1181 - 1190 of 10000 in total
  1. Drug

    Ixazomib

    go.drugbank.com/drugs/DB09570
    ApprovedInvestigational

    Ixazomib is a reversible proteasome inhibitor. Because it is a modified peptide boronic acid with one chiral center,[A264329] it is considered a boronate proteasome inhibitor. … [A7948] More than 99% of the drug compound is the R-enantiomer.[A264329] Ixazomib was approved by the FDA on November 20, 2015, making it the first oral proteasome inhibitor approved in the US.

    Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-5-oxo-1,3,2-dioxaborolane-4,4-diacetic acid, BORONIC ACID, B-((1R)-1-((2-((2,5-DICHLOROBENZOYL)AMINO)ACETYL)AMINO)-3-METHYLBUTYL)-
  2. Drug

    AVS-100

    go.drugbank.com/drugs/DB18068
    Experimental

    Synonyms: 3-Isoxazolecarboxamide, 5-[2-[(3,4-dichlorobenzoyl)amino]ethyl]-N-hydroxy-, 5-[2-[(3,4-dichlorobenzoyl)amino]ethyl]-N-hydroxy-3-isoxazolecarboxamide
  3. Drug

    4-Nitrocatechol sulfate

    go.drugbank.com/drugs/DB01800
    Experimental

    Synonyms: 2-Hydroxy-5-nitrophenyl sulfate, 2-hydroxy-5-nitrophenyl hydrogen sulfate
  4. Drug

    2',3'-Dideoxyadenosine triphosphate

    go.drugbank.com/drugs/DB02189
    Experimental

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 2',3'-dideoxyadenosine 5'-triphosphate, Dideoxyadenosine 5'-triphosphate
  5. Drug

    N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide

    go.drugbank.com/drugs/DB06944
    Experimental

    N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide is a solid. This compound belongs to the naphthalenes. … The proteins that N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide targets include cyclin-A2 and cyclin-dependent kinase 2.

    Synonyms: N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide
  6. Drug

    Simpinicline

    go.drugbank.com/drugs/DB17065
    Investigational

    Synonyms: Pyrimidine, 5-((1e)-2-(3r)-3-pyrrolidinylethenyl)-
  7. Drug

    1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLTHIO)PYRIMIDINE-2,4(1H,3H)-DIONE

    go.drugbank.com/drugs/DB06872
    Experimental

    Synonyms: 1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLTHIO)PYRIMIDINE-2,4(1H,3H)-DIONE
  8. Drug

    N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE

    go.drugbank.com/drugs/DB08454
    Experimental

    Synonyms: N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE
  9. Drug

    4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE

    go.drugbank.com/drugs/DB08572
    Experimental

    Synonyms: 4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE
  10. Drug

    1-(5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)-2-(METHYLAMINO)ETHANONE

    go.drugbank.com/drugs/DB08576
    Experimental

    Synonyms: 1-(5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)-2-(METHYLAMINO)ETHANONE