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TN-201
go.drugbank.com/drugs/DB18700InvestigationalTN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene.
Synonyms: Native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 geneNendratareotide uzatansine
go.drugbank.com/drugs/DB18351InvestigationalNendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated to the cytotoxin mertansine.
Synonyms: Peptide-drug conjugate combining [(Tyr3,Cys8) octreotate amide] and N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl) maytansineTRK-001
go.drugbank.com/drugs/DB18577InvestigationalTRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Synonyms: Natural Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), Rapamycin and Transforming Growth Factor-betaCLL1-CD33 compound chimeric antigen receptor T cells
go.drugbank.com/drugs/DB18568InvestigationalSynonyms: Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33DT-DEC01
go.drugbank.com/drugs/DB19433ExperimentalDT-DEC01 is a novel Dystrophin Expressing Chimeric (DEC) cell therapy being investigated by Dystrogen Therapeutics Corporation.
Synonyms: Dystrophin Expressing Chimeric Cells derived from allogenic normal human myoblast and autologous DMD myoblast from Duchenne muscular dystrophy affected donorPosoleucel
go.drugbank.com/drugs/DB17974InvestigationalSynonyms: Allogeneic multi-virus specific T lymphocytes targeting BK virus, cytomegalovirus, human herpes virus-6, Epstein Barr virus, and adenovirusPEP0101
go.drugbank.com/drugs/DB18572ExperimentalPEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Synonyms: Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and an elastin-like polypeptide drug carrier.TVI-Brain-1
go.drugbank.com/drugs/DB17227InvestigationalSynonyms: Attenuated autologous cancer cells and granulocyte macrophage colony stimulating factor in combination with activated autologous blood derived T-cellsHiltonol
go.drugbank.com/drugs/DB17293InvestigationalSynonyms: 5'-cytidylic acid, homopolymer, complex with 5'-inosinic acid homopolymer (1:1), compd. with cellulose carboxymethyl ether and l-lysine homopolymer, L-lysine, homopolymer, compd. with cellulose carboxymethyl ether and 5'-inosinic acid homopolymer complex with 5'-cytidylic acid homopolymerCategories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsPacanalotamab
go.drugbank.com/drugs/DB17254InvestigationalSynonyms: Bispecific t-cell engager antibody with a single chain fc moiety that binds to b cell maturation antigen surface receptor and cd3