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DCLL-9718S
go.drugbank.com/drugs/DB17392InvestigationalDCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1).
Synonyms: THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and DNA alkylating cross-linking agent pyrrolo [2,1-c][1,4] benzodiazepine dimerCategories: Amino Acids, Peptides, and ProteinsRaxtozinameran
go.drugbank.com/drugs/DB18228ApprovedInvestigationalRaxtozinameran is also known as Pfizer-BioNTech COVID-19 Vaccine and Comirnaty. … [A273680] Raxtozinameran was first approved by the FDA and EMA through emergency use in December 2020.[L52565,L39272]
Synonyms: messenger RNA (mRNA), 5'-capped, encoding a full-length, codon-optimised pre-fusion stabilised conformation variant (K982P and V983P) of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)Tepilamide fumarate
go.drugbank.com/drugs/DB18804InvestigationalSynonyms: 2-(diethylamino)-2-oxoethyl and methyl (2e)-but-2-enedioateDabocemagene autoficel
go.drugbank.com/drugs/DB17878InvestigationalDabocemagene autoficel is an _ex vivo_, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen.
Synonyms: AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING, SELF-INACTIVATING LENTIVIRUS VECTOR THAT ENCODES HUMAN COLLAGEN TYPE VII ALPHA 1 (COL7A1) UNDER, 2004-TRANSDUCED HUMAN AUTOLOGOUS DYSTROPHIC EPIDERMOLYSIS BULLOSA DERMAL FIBROBLAST CELL FCX-007 INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-ANDGinsenoside Rd
go.drugbank.com/drugs/DB19256InvestigationalGinsenoside Rd is under investigation in clinical trial NCT00815763 (Efficacy and Safety of Ginsenoside-rd for Acute Ischemic Stroke).
Synonyms: Ginsenoside Rd (constituent of american ginseng, asian ginseng, and tienchi ginseng)PRGN-3006
go.drugbank.com/drugs/DB17229InvestigationalPRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface
Synonyms: Autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and a truncated form of human HER1t (kill switch) on the cell surfaceSTRO-001
go.drugbank.com/drugs/DB17224InvestigationalSynonyms: antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable maytansinoid linker warheadsSurovatamig
go.drugbank.com/drugs/DB19420InvestigationalTNB-486 is under investigation in clinical trial NCT06564038 (A Study of AZD0486 Monotherapy or in Combination With Other Anti-cancer Agents for Mature B-cell Malignancies).
Synonyms: sapiens and humanized monoclonal antibody asymetric,, immunoglobulin (H-gamma4_L-kappa)_VH-G4(h-CH2-CH3), anti-[Homo sapiens CD3D (CD3 delta) and CD3E (CD3 epsilon, Leu-4) dimer] and anti-[Homo sapiens CD19 (B lymphocyte surface antigen B4, Leu-12)], HomoDemplatin pegraglumer
go.drugbank.com/drugs/DB14807InvestigationalDemplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Categories: Amino Acids, Peptides, and ProteinsSynonyms: A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl linkagecisplatin is incorporated in polymeric micelles via polymer-metal complex formation withGarcinia gummi-gutta fruit
go.drugbank.com/drugs/DB14365InvestigationalIt is not an approved drug.
Synonyms: Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica)