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AOC-1020
go.drugbank.com/drugs/DB18621InvestigationalAOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded
Synonyms: An antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotideLawsonia inermis leaf
go.drugbank.com/drugs/DB14313InvestigationalIt is not an approved drug.
Categories: Non-Standardized Plant Allergenic ExtractSynonyms: Plants and Plant Parts, Henna Lawsonia InermisTepilamide fumarate
go.drugbank.com/drugs/DB18804InvestigationalSynonyms: 2-(diethylamino)-2-oxoethyl and methyl (2e)-but-2-enedioate, (n,n-diethylcarbamoyl)methyl methyl (2e)-but-2-ene-1,4-dioateTifcemalimab
go.drugbank.com/drugs/DB18914InvestigationalTifcemalimab is under investigation in clinical trial NCT06095583 (Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)).
Synonyms: Immunoglobulin g4, anti-(human b and t lymphocyte attenuator (btla)) (human-mus musculus monoclonal js004 .gamma.4-chain), disulfide with human-mus musculus monoclonal js004 .kappa.-chain, dimerAD-214
go.drugbank.com/drugs/DB18412InvestigationalSynonyms: Fc-fusion protein comprised of an anti-CXCR4 i-body tethered at its C-terminus to constant domains 2 and 3 of the Fc region of a mutated human IgG1Lym-1-I-131
go.drugbank.com/drugs/DB17445ExperimentalLym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant lymphocytes.
Synonyms: Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphomaEtigilimab
go.drugbank.com/drugs/DB18854InvestigationalEtigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).
Synonyms: Immunoglobulin g1, anti-(human receptor tigit(t-cell immunoreceptor with ig and itim domains)) (humanized mouse monoclonal omp-313m32 .gamma.1-chain), disulfide with humanized mouse monoclonal omp-313m32Lorigerlimab
go.drugbank.com/drugs/DB18942InvestigationalLorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-resistant Prostate Cancer).
Synonyms: HOMO SAPIENS AND HUMANIZED MONOCLONAL ANTIBODY, TET, MMUNOGLOBULIN G4 SCFV-H-CH2-CH3_SCFV, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD1, PD-1, CD279)) AND ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), CHIMERIC,Acapatamab
go.drugbank.com/drugs/DB18838InvestigationalAcapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Synonyms: Mmunoglobulin scfv-scfv-scfc, anti-(homo sapiens folh1 (folate hydrolase, prostate specific membrane antigen, psma)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chainCibisatamab
go.drugbank.com/drugs/DB17349InvestigationalSynonyms: Humanized immunoglobulin g1 (igg1) t-cell bispecific (tcb) antibody targeting carcinoembryonic antigen (cea) and cd3 epsilon chain (cd3e) on t-cellsCategories: Amino Acids, Peptides, and Proteins