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Etofamide
go.drugbank.com/drugs/DB13258ApprovedEtofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued [L5617].
Dienogest
go.drugbank.com/drugs/DB09123ApprovedInvestigationalIt is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not available in the US by itself.
Mixtures: ARIORA 1MG/2MG, ARIORA 1MG/2MGSegesterone acetate
go.drugbank.com/drugs/DB14583ApprovedSegesterone acetate is not an orally active compound, but it is proved to be a potent anti-ovulatory agent when given in implants, vaginal rings or percutaneous gel [A37090]. … On August 10, 2018, Annovera™ containing segesterone acetate and [ethinyl estradiol] was granted approval by the U.S.
Dalbavancin
go.drugbank.com/drugs/DB06219ApprovedInvestigationalModifications from these older glycoprotein classes facilitated a similar mechanism of action for dalbavancin but with increased activity and once-weekly dosing [FDA Label, F2356, A4072, A4073]. … Dalbavancin acts by interfering with bacterial cell wall synthesis by binding to the D-alanyl-D-alanine terminus of nascent cell wall peptidoglycan and preventing cross-linking [FDA Label, F2356, A4072
Palonosetron
go.drugbank.com/drugs/DB00377ApprovedInvestigationalHT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of its class approved for this use by
Mixtures: AKYNZEO CAPSULES 300MG/0.5MG, Akynzeo (netupitant/palonosetron) 300mg/0.5mg Hard CapsulesGanaxolone
go.drugbank.com/drugs/DB05087ApprovedInvestigational[L41135] In July 2023, ganaxolone was also approved under the same brand name and for the same indication by the EMA.[L47636] … [L41130] It was approved under the brand name ZTALMY by the US FDA in March 2022 for the treatment of seizures associated with CDKL5 deficiency disorder (CDD), becoming the first FDA-approved treatment
Raxtozinameran
go.drugbank.com/drugs/DB18228ApprovedInvestigational[A273680] Raxtozinameran was first approved by the FDA and EMA through emergency use in December 2020.[L52565,L39272] … It works by binding to the spike (S) protein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which is a transmembrane glycoprotein that plays a vital role in viral pathogenesis, evolutions
Delapril
go.drugbank.com/drugs/DB13312InvestigationalMixtures: VIVACE 30/10MG TABLETTEN, VIVACE 30/10MG TABLETTENFluprednidene acetate
go.drugbank.com/drugs/DB14634InvestigationalFluprednidene acetate is a corticosteroid. It has anti-inflammatory and anti-allergic properties.
Mixtures: Vobaderm 1mg/g + 20mg/g CremeTrihexyphenidyl
go.drugbank.com/drugs/DB00376ApprovedInvestigational[L31843] It has largely been replaced by drugs such as [levodopa].[L31843] Trihexyphenidyl was granted FDA approval on 13 May 1949.[L31768]