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Acellular nerve allograft
go.drugbank.com/drugs/DB30293ApprovedInvestigationalApproved by the FDA under a Biologics License Application (BLA) as an acellular nerve scaffold for the treatment of adult and pediatric patients (aged ≥1 month) with sensory, mixed, and motor peripheral … Our team is working on the full update, which will be available soon. [L54673,L54668]
Naloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approvedHowever, for individuals using opioid medications or experiencing an overdose, IM injection of naloxone rapidly reverses opioid effects and can cause the injected individual to immediately experience withdrawal … [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors.
Mixtures: TILIDIN 100/8 RETARD 1A PH, TILIDIN 100/8 RETARD 1A PHCategories: Drugs for Constipation, Peripheral Opioid Receptor AntagonistsHormone Receptor Positive Metastatic Breast Cancer
go.drugbank.com/conditions/DBCOND0120563Synonyms: Hormone Receptor-positive Metastatic Breast Cancer, Hormone Receptor Positive Metastatic Breast CancerPicosulfuric acid
go.drugbank.com/drugs/DB09268ApprovedInvestigationalThe combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian market in 2005 and has been used in European countries for many years.[A33322]
Mixtures: PICOPREP Powder for Oral Solution, PICO-SALAX Powder for Oral SolutionCategories: Drugs for ConstipationHydroxyprogesterone caproate
go.drugbank.com/drugs/DB06789ApprovedIt is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). … FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a history of preterm delivery, sparking a pricing controversy
Categories: Hormonal Contraceptives for Systemic Use, Cytochrome P-450 SubstratesPropyl alcohol
go.drugbank.com/drugs/DB03175ApprovedA colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.
Mixtures: Softa-Man Cutaneous Solution, Aseptoderm Pur Lösung zur Anwendung auf der HautReslizumab
go.drugbank.com/drugs/DB06602ApprovedInvestigationalCinqair is indicated as an add-on maintenance therapy for adults with severe asthma with an eosinophilic phenotype. … risk for recurrent exacerbation and asthma-related hospitalizations [A31579].
Categories: Drugs for Obstructive Airway DiseasesClozapine
go.drugbank.com/drugs/DB00363ApprovedInvestigational[A256718] Clozapine was approved by the FDA in 1989 for treatment-resistant schizophrenia under the brand CLOZARIL. … Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesClofazimine
go.drugbank.com/drugs/DB00845ApprovedInvestigationalWithdrawnClofazimine is a highly lipophilic antimicrobial riminophenazine dye used in combination with other agents, such as [dapsone], for the treatment of leprosy. … [A203144] Although it carries _in vitro_ activity against other mycobacterium, such as _Mycobacterium tuberculosis_, it is generally considered an ineffective treatment in comparison to classic tuberculosis
Categories: Antiinfectives for Systemic Use, Drugs for Treatment of LepraClonazepam
go.drugbank.com/drugs/DB01068ApprovedIllicitInvestigationalA benzodiazepine used to treat various seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. … [FDA Label][L5572,F3763,F3787,F3796] The agent has also been indicated for treating panic disorder.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 Inhibitors