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Iodide I-131
go.drugbank.com/drugs/DB09293ApprovedInvestigationalTherapeutic solutions of Sodium Iodide-131 are indicated for the treatment of hyperthyroidism and thyroid carcinomas that take up iodine. … Because the thyroid gland naturally takes up iodine from the body, therapeutic methods using radioisotopes can take advantage of this mechanism for localization of drug to the site of malignancy.
Ioxaglic acid
go.drugbank.com/drugs/DB09313ApprovedWithdrawnIoxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast agents [L1883].
Categories: Compounds used in a research, industrial, or household settingVoxelotor
go.drugbank.com/drugs/DB14975ApprovedVoxelotor is a novel hemoglobin S polymerization inhibitor for the treatment of sickle cell disease. … The EMA approved the use of voxelotor for the treatment of hemolytic anemia associated with sickle cell disease in February 2022.[L41419,L41424]
Pheniramine
go.drugbank.com/drugs/DB01620ApprovedPheniramine is a first-generation antihistamine in the alkylamine class, similar to brompheniramine and chlorpheniramine. It is used in some over-the-counter allergy as well as cold & flu products in combination with other drugs. Phe...
Mixtures: Hot Lemon for Colds Powder, Hot Lemon Relief for Cold Symptoms PwsCategories: Antihistamines for Systemic Use, Antihistamines for Topical UseAnakinra
go.drugbank.com/drugs/DB00026ApprovedInvestigational[L35415] Anakinra is indicated for the management of rheumatoid arthritis (RA) in patients 18 years of age or older who have failed one or more disease-modifying antirheumatic drugs (DMARDs), as well as … On November 14, 2001, it was approved by the FDA for the treatment of rheumatoid arthritis.
Categories: Biologics for Rheumatoid Arthritis TreatmentSulfadimethoxine
go.drugbank.com/drugs/DB06150ApprovedVet approvedWithdrawnIn the US, sulfadimethoxine is one of the products that have been withdrawn or removed from the market after being found to be unsafe or not effective.[L43942] … Sulfadimethoxine is approved in Russia for use in humans, including children, and has been successfully used there for more than 35 years.
Mixtures: Hampiseptol Solution For InjectionCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigational[A1320] Sirolimus was first approved by the FDA in 1999 for the prophylaxis of organ rejection in patients aged 13 years and older receiving renal transplants. … [A242372] The topical formulation of sirolimus, marketed as HYFTOR, was approved by the FDA in April 2022: this marks the first topical treatment approved in the US for facial angiofibroma associated with
Linaclotide
go.drugbank.com/drugs/DB08890ApprovedInvestigational[A260286] Linaclotide is used for the treatment of various types of constipation, including irritable bowel syndrome with constipation. Linaclotide was first approved by the FDA on August 30, 2012.
Categories: Drugs for ConstipationRemestemcel-L
go.drugbank.com/drugs/DB13973ApprovedInvestigationalWithdrawnIt was approved for use in Canada in May 2012 as Prochymal for the management of refractory acute Graft versus Host Disease (aGvHD) in children who are unresponsive to systemic steroid therapies, with … Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells intended for intravenous infusion.
Insulin lispro
go.drugbank.com/drugs/DB00046ApprovedInvestigationalbetween meals or overnight. … Absorption of glucose into cells allows for its transformation into glycogen or fat for storage.
Mixtures: HUMALOG MIX 25 SUSPENSION FOR INJECTION 100 iu/ml, HUMALOG MIX 25 SUSPENSION FOR INJECTION 100 iu/mlCategories: Insulins and Analogues for Injection, Fast-Acting