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Displaying results 1231 - 1240 of 10000 in total
  1. Drug

    Ergocalciferol

    go.drugbank.com/drugs/DB00153
    ApprovedInvestigationalNutraceutical

    Ergocalciferol is an inactivated vitamin D analog.[A177526] It is synthesized by some plants in the presence of UVB light. … These modifications reduce the affinity of ergocalciferol for the vitamin D binding protein resulting in faster clearance, limits its activation, and alters its catabolism.

    Synonyms: Vitamin D 2, Vitamin D-2Mixtures: Calcium Mg and Zn Capsules With Vitamin D, Mvc 9+4 Inj
  2. Drug

    Escitalopram

    go.drugbank.com/drugs/DB01175
    ApprovedInvestigational

    [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. … as compared to other agents in this class.

    Synonyms: (S)-Citalopram, S(+)-CitalopramCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Combined Inhibitors of Serotonin/Norepinephrine Reuptake
  3. Drug

    Polyethylene glycol

    go.drugbank.com/drugs/DB09287
    ApprovedInvestigationalVet approved

    [L11812] PEG 3350 is also used for cleansing of the colon in preparation for colonoscopy in adults. … cleansing for preparation in colonoscopy.

    Mixtures: Gavilyte-N, Bi-peglyteCategories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitors
  4. Drug

    Ketotifen

    go.drugbank.com/drugs/DB00920
    ApprovedInvestigational

    [A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of itchy eyes associated with allergies,[L32278] and in Canada a prescription-only oral formulation is … [A231204] Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis.

    Categories: Heterocyclic Compounds, 1-RingProducts: CHETOTIFENE MYLAN GENERICS, Zaditen konservierungsmittelfrei 0,025% - Augentropfen in Einzeldosisbehältnissen
  5. Drug

    Ipilimumab

    go.drugbank.com/drugs/DB06186
    ApprovedInvestigational

    [L12126] Ipilimumab was granted FDA approval on 25 March 2011.[L12126] … Ipilimumab is a fully humanized IgG1 monoclonal antibody that blocks cytotoxic T lymphocyte antigen-4 (CTLA-4).

    Categories: Immunoglobulin G, CTLA-4-directed Blocking AntibodyProducts: YERVOY 200MG/40ML IV INFUZYONLUK ÇOZELTI KONSANTRESI ICEREN FLAKON, 1 ADET, YERVOY 50MG/10ML IV INFUZYONLUK ÇOZELTI KONSANTRESI ICEREN FLAKON, 1 ADET
  6. Drug

    Methoxy PEG-12 retinamide

    go.drugbank.com/drugs/DB14142
    Investigational

    Synonyms: Medimin AProducts: O Hui Wrinkle Science Wrinkle Repair Serum
  7. Drug

    Memantine

    go.drugbank.com/drugs/DB01043
    ApprovedInvestigational

    Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). … Memantine blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability and excessive stimulation in Alzheimer's Disease [T556].

    Synonyms: 1-Amino-3,5-dimethyladamantane, 1,3-Dimethyl-5-adamantanamineMixtures: EMAXIN BASLANGIC SETI, 7+7+7+7 ADET, EMAXIN BASLANGIC SETI, 7+7+7+7 ADET
  8. Drug

    Thiotepa

    go.drugbank.com/drugs/DB04572
    ApprovedInvestigational

    N,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years. … It is a stable derivative of N,N',N''- triethylenephosphoramide (TEPA). It is mostly used to treat breast cancer, ovarian cancer and bladder cancer.

    Synonyms: N,N′,N′′-tri-1,2-ethanediyl-, Phosphorothioic triamide, N,N′,N′′-tri-1,2-ethanediyl-Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 Substrates
  9. Drug

    Budesonide

    go.drugbank.com/drugs/DB01222
    ApprovedInvestigational

    [A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598] It is also available in a combination product with [formoterol].[L10619] … Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.

    Mixtures: SYMBICORT TUR160UG/D 120ED, SYMBICORT TURBO160/4.5UG/DCategories: Agents to Treat Airway Disease, P-glycoprotein substrates
  10. Drug

    Voriconazole

    go.drugbank.com/drugs/DB00582
    ApprovedInvestigational

    [L15571] It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. … Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections.

    Categories: Metabolic Side Effects of Drugs and Substances, Cytochrome P-450 SubstratesSynonyms: (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol, (αR,βS)-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol