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Displaying results 1251 - 1260 of 9689 in total
  1. Drug

    ATG-101

    go.drugbank.com/drugs/DB17162
    Investigational

    ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors

    Synonyms: PD-L1/4-1BB bispecific antibody
  2. Drug

    Ixazomib

    go.drugbank.com/drugs/DB09570
    ApprovedInvestigational

    Ixazomib is a reversible proteasome inhibitor. Because it is a modified peptide boronic acid with one chiral center,[A264329] it is considered a boronate proteasome inhibitor. … [L51244] It was also investigated in other hematological malignancies as well as other conditions, such as systemic light chain (AL) amyloidosis, graft-versus-host disease, and lupus nephritis.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index
  3. Drug

    Ivermectin

    go.drugbank.com/drugs/DB00602
    ApprovedInvestigationalVet approved

    [L31453] Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A<sub>1a</sub> (22,23-dihydroavermectin B<sub>1a</sub>) and 10% 5-O-demethyl-25-de … (1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A<sub>1a</sub> (22,23-dihydroavermectin B<sub>1b</sub>).

    Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    Nerinetide

    go.drugbank.com/drugs/DB12595
    Investigational

    Na 1 is under investigation in clinical trial NCT00728182 (Evaluating Neuroprotection in Aneurysm Coiling Therapy).

    Synonyms: L-TYROSYLGLYCYL-L-ARGINYL-L-LYSYL-L-LYSYL-L-ARGINYL-L-ARGINYL-L-GLUTAMINYL-L-ARGINYL-L-ARGINYL-L-ARGINYL-L-LYSYL-L-LEUCYL-L-SERYL-L-SERYL-L-ISOLEUCYL-L-.ALPHA.-GLUTAMYL-L-SERYL-L-.ALPHA., L-VALINE, L-TYROSYLGLYCYL-L-ARGINYL-L-LYSYL-L-LYSYL-L-ARGINYL-L-ARGINYL-L-GLUTAMINYL-L-ARGINYL-L-ARGINYL-L-ARGINYL-L-LYSYL-L-LEUCYL-L-SERYL-L-SERYL-L-ISOLEUCYL-L-.ALPHA.-GLUTAMYL-L-SERYL-L-.ALPHA.
  5. Drug

    Cefoselis

    go.drugbank.com/drugs/DB19513
    Experimental

    Cefoselis is a small molecule drug. Cefoselis has a monoisotopic molecular weight of 522.11 Da.

  6. Drug

    Elisidepsin

    go.drugbank.com/drugs/DB19522
    Experimental

    Elisidepsin is a small molecule drug. Elisidepsin has a monoisotopic molecular weight of 1476.93 Da.

  7. Drug

    Cargutocin

    go.drugbank.com/drugs/DB19643
    Experimental

    Cargutocin is a small molecule drug. Cargutocin has a monoisotopic molecular weight of 915.48 Da.

  8. Drug

    Cyprolidol

    go.drugbank.com/drugs/DB19771
    Experimental

    Cyprolidol is a small molecule drug. Cyprolidol has a monoisotopic molecular weight of 301.15 Da.

  9. Drug

    Pamicogrel

    go.drugbank.com/drugs/DB19812
    Experimental

    Pamicogrel is a small molecule drug. Pamicogrel has a monoisotopic molecular weight of 448.15 Da.

  10. Drug

    Nobiprostolan

    go.drugbank.com/drugs/DB19814
    Experimental

    Nobiprostolan is a small molecule drug. Nobiprostolan has a monoisotopic molecular weight of 468.35 Da.