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Brecanavir
go.drugbank.com/drugs/DB04887InvestigationalBrecanavir (VX-385) an orally active aspartic protease inhibitor (PI), under investigation by Vertex and GlaxoSmithKline for the treatment of HIV.
Azintuxizumab vedotin
go.drugbank.com/drugs/DB14847Investigationalis under investigation in clinical trial NCT02951117 (A Study of Venetoclax and ABBV-838 Combination Therapy With Dexamethasone in Participants With Multiple Myeloma Whose Cancer Has Come Back or Had No
Ridogrel
go.drugbank.com/drugs/DB01207ExperimentalHowever, there currently are no clinical indications for preferential use of ridogrel over aspirin.
SR-9011
go.drugbank.com/drugs/DB14014ExperimentalSR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues
Synonyms: 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-Suramin
go.drugbank.com/drugs/DB04786InvestigationalA polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluati...
Entrectinib
go.drugbank.com/drugs/DB11986ApprovedInvestigationalEntrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019 for use in the treatment...
Synonyms: N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamideCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesTaurocholic acid
go.drugbank.com/drugs/DB04348ApprovedThe product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagog...
Mixtures: Herbalax Forte No 70 TabCategories: P-glycoprotein inhibitors, P-glycoprotein substratesPlant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine
go.drugbank.com/drugs/DB16757Approved[A245824] In addition, VLPs contain no viral material and are therefore inherently non-infectious, making them potentially safer alternatives to traditional vaccines.[A245824]
Chikungunya vaccine (live, attenuated)
go.drugbank.com/drugs/DB18701ApprovedInvestigational[L48786] There are no approved treatments for active chikungunya virus infection.