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Verapamil
go.drugbank.com/drugs/DB00661ApprovedInvestigationalVerapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a m...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Verelan PM, Verapamil Hydrochloride PMBrimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigationalBrimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 ...
Mixtures: Brim-Dor PF, Tim-Brim-Dor PFProducts: Alphagan P, ALPHAGAN PItopride
go.drugbank.com/drugs/DB04924InvestigationalItopride is a dopamine D2 antagonist with acetylcholinesterase inhibitory actions.
Synonyms: N-(p-(2-(Dimethylamino)ethoxy)benzyl)veratramideProducts: DOIZ 50 MG FC TABLETBenzocaine
go.drugbank.com/drugs/DB01086ApprovedInvestigationalBenzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products. Benzocaine was first used for l...
Mixtures: SUFREXAL P, PM Toothache ReliefCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesBenserazide
go.drugbank.com/drugs/DB12783ApprovedInvestigationalThis can result in a number of side effects like nausea, vomiting, or even cardiac arrhythmias that may diminish patient adherence [F2, L2553]. … Moreover, the European Medcines Agency has conferred an orphan designation upon benseraside since 2015 for its potential to be used as a therapy for beta thalassaemia as well [F3].
Mixtures: LEVODOPA P BENS AL 100/25, LEVODOPA P BENS AL 100/25Simvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigationalstatin medications are considered equally effective from a clinical standpoint, [rosuvastatin] is considered the most potent; doses of 10 to 40mg [rosuvastatin] per day were found in clinical studies to result
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: VASCOR TABLET 40MG F/C, VASCOR TABLET 20MG F/CAlfacalcidol
go.drugbank.com/drugs/DB01436ApprovedInvestigationalNutraceuticalAlfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of vitamin D. It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 2...
Products: PP Alfa-DOL 1.00 mcg CapsuleCetirizine
go.drugbank.com/drugs/DB00341ApprovedInvestigationalCetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other sympt...
Mixtures: FLUZETRIN F GOTAS, CHALVER FLUZETRIN®F JARABECategories: P-glycoprotein inhibitors, P-glycoprotein substratesFebuxostat
go.drugbank.com/drugs/DB04854ApprovedInvestigationalFebuxostat is a non-purine xanthine oxidase (XO) inhibitor. In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. In the following year, the FDA for ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: FEBUXOSTAT ZENTIVA 80MG FTLipoic acid
go.drugbank.com/drugs/DB00166ApprovedInvestigationalNutraceuticalA vitamin-like antioxidant.
Products: LIPONSAEURE RATIO 600MG PI