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Heparin
go.drugbank.com/drugs/DB01109ApprovedInvestigationalIt binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa.
Mixtures: HEPARINISED SALINE INJECTION 10 iu/mlProducts: /ML., Unihepa 1000 IU/ ml Injection (5 ml vial)Anakinra
go.drugbank.com/drugs/DB00026ApprovedInvestigationalAnakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino acid residues. … This drug binds to the IL-1 receptor, competing with and inhibiting the activity of IL-1 alpha and beta.
Synonyms: IL-1RAProducts: Kıneret 100 mg/ 0.67 ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör, 7 ADET, Kıneret 100 mg/ 0.67 ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör, 28 ADETInsulin human
go.drugbank.com/drugs/DB00030ApprovedInvestigationalHuman Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to end...
Mixtures: GENSULIN M 40 (40/60) 100 IU/ML, GENSULIN M 40 (40/60) 100 IU/MLProducts: LANTUS XR, Humulin LNemolizumab
go.drugbank.com/drugs/DB15252ApprovedInvestigational[A264254] By binding to IL-31RA, nemolizumab blocks the IL-31 signalling cascades that lead to inflammation. … Nemolizumab is a humanized monoclonal modified immunoglobulin 2 (IgG2) antibody directed against interleukin-31 receptor alpha (IL-31RA),[L51159] which is an endogenous cytokine implicated in the pathophysiology
Lacosamide
go.drugbank.com/drugs/DB06218ApprovedInvestigationalLacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of intera...
Products: Motpoly XR, ELEPSI 10 MG/ML ŞURUP,200 ML ŞIŞEUstekinumab
go.drugbank.com/drugs/DB05679ApprovedInvestigationalUstekinumab is currently the first and only approved biologic therapy for ulcerative colitis that targets the interleukin (IL)-12 and IL-23 cytokines. … Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses.
Products: STELARA® 90 MG/ML, STELARA® 45 MG/0.5 MLDL-dimyristoylphosphatidylcholine
go.drugbank.com/drugs/DB11283ApprovedA synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. It is used in commercial drug preparations to solubilize drugs for injection
Synonyms: DL-dimyristoylphosphatidylcholine, Dimyristoylphosphatidylcholine, DL-Benralizumab
go.drugbank.com/drugs/DB12023ApprovedInvestigational[A31294] It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta subunits of the IL-5R, thus blocking signal transduction. … Benralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils
Products: FASENRA SOLUTION FOR INJECTION 30MG/ML (PRE-FILLED SYRINGE), FASENRA SOLUTION FOR INJECTION 30MG/ML (AUTOINJECTOR PEN)Tralokinumab
go.drugbank.com/drugs/DB12169ApprovedInvestigational[A242427] Tralokinumab is a fully human IgG4 monoclonal antibody targeted against IL-13. … It neutralizes IL-13 activity by inhibiting its ability to bind with receptors, thus helping to alleviate AD symptoms.
Rilonacept
go.drugbank.com/drugs/DB06372ApprovedInvestigationalRilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1.
Synonyms: IL-1 TRAP, IL-1-TRAP