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Colestipol
go.drugbank.com/drugs/DB00375Approved[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia … not be good candidates for using the agent owing to its physical effects on the gut.
Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaHelium
go.drugbank.com/drugs/DB09155ApprovedInvestigationalVet approvedIt is also used as an analytical reagent in diagnostic/imaging tests to detect respiratory function of the patient.
Mixtures: iCOmix 0,28 % / 9,3 % Gas zur medizinischen Anwendung, druckverdichtetAtoltivimab
go.drugbank.com/drugs/DB15898ApprovedInvestigational[A221825, A221830] A recent large-scale study elucidated that both neutralizing and Fc-mediated functions of antibodies were important for therapeutic benefit in animal models of EBOV infection. … Ebola virus (EBOV) remains an important human pathogen within the _Ebolavirus_ genus, having been responsible for at least 17 known outbreaks with an average case fatality rate of 43.92%.
Categories: Treatments for Ebola Virus DiseaseMagnesium Aluminum Silicate
go.drugbank.com/drugs/DB11230ApprovedWithdrawnIt is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking agent, opacifying agent, viscosity-increasing agent, suspending agent, tablet and capsule disintegrant
Acetylcarnitine
go.drugbank.com/drugs/DB08842ApprovedInvestigationalThe main role of acetylcarnitine is to help transport fatty acids into the mitochondrial matrix where fatty acid metabolism occurs. … Acetylcarnitine can be synthesized, but it is also naturally found in adequate amounts in healthy humans.
Categories: Psychostimulants, Agents Used for ADHD and NootropicsOlaparib
go.drugbank.com/drugs/DB09074ApprovedInvestigationalOlaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2. PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in c...
Categories: Cytochrome P-450 CYP2B6 Inducers, P-glycoprotein inhibitorsCarbon monoxide
go.drugbank.com/drugs/DB11588ApprovedInvestigationalCarbon monoxide is presently used in small amounts in low oxygen modified atmosphere packaging systems (MAP) for fresh meat to stabilize and maintain natural meat color. … The technique was first described 100 years ago, and applied to clinical practice many years after.
Mixtures: iCOmix 0,28 % / 9,3 % Gas zur medizinischen Anwendung, druckverdichtet, iCOmas 0,3 % / 0,3 % / 0,3 % Gas zur medizinischen Anwendung, druckverdichtetPotassium hydroxide
go.drugbank.com/drugs/DB11153ApprovedPotassium hydroxide is used in food to adjust pH, as a stabilizer, and as a thickening agent. … Recently, it has been studied for efficacy and tolerability in the treatment of warts.
Mixtures: Nutriflex Peri Solution for InfusionVosoritide
go.drugbank.com/drugs/DB11928ApprovedInvestigationalEndogenous CNP, first described in 1998, is primarily responsible for the stimulation of chondrocytes and long bone growth via activity at the NPR-B receptor, making it an attractive target in the treatment … approved for the treatment of achondroplasia in both regions.
Categories: Drugs for Treatment of Bone DiseasesIdelalisib
go.drugbank.com/drugs/DB09054ApprovedInvestigationalFor the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab alone would be considered appropriate therapy due to other … More specifically, idelalisib targets P110δ, the delta isoform of the enzyme phosphatidylinositol-4,5-bisphosphate 3-kinase, also known as PI-3K.
Categories: P-glycoprotein inhibitors, P-glycoprotein substrates