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Displaying results 131 - 140 of 449 in total
  1. Drug

    Becotatug

    go.drugbank.com/drugs/DB19069
    Investigational

    Becotatug is under investigation in clinical trial NCT06380348 (JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by E...

    Synonyms: Immunoglobulin G1, anti-(human epidermal growth factor receptor) (human-Mus musculus monoclonal JMT101 γ1-chain), disulfide with human-Mus musculus monoclonal JMT101 κ-chain, dimer, Jmt101 (fully human monoclonal igg1 antibody targeting epidermal growth factor receptor (egfr))
  2. Drug

    Xaluritamig

    go.drugbank.com/drugs/DB18137
    Investigational

    Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.

    Synonyms: Immunoglobulin G1 Fab fragment [218-lysine], anti-(human metalloproteinase STEAP1) (human-Mus musculus clone 2F3.013 N67Q γ1-chain) fusion protein with peptide linker (GGGGS)2 fusion protein with immunoglobulin, anti-(human CD3 antigen) (human-Mus muscul
  3. Drug

    Livmoniplimab

    go.drugbank.com/drugs/DB18939
    Investigational

    Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination

    Synonyms: Immunoglobulin g4 (234-proline), anti-(human protein garp-transforming growth factor .beta.1 complex) (human monoclonal abbv-151 .gamma.4-chain), disulfide with human monoclonal abbv-151 .kappa.
  4. Drug

    Finotonlimab

    go.drugbank.com/drugs/DB18859
    Investigational

    Finotonlimab is under investigation in clinical trial NCT04560894 (SCT-I10A Plus SCT510 Versus Sorafenib as First-line Therapy for Advanced Hepatocellular Carcinoma).

    Synonyms: Immunoglobulin g4 (226-proline), anti-(human programmed cell death 1) (human-mus musculus monoclonal sct-i10a .gamma.4-chain), disulfide with human-mus musculus monoclonal sct-i10a .kappa.
  5. Drug

    Teropavimab

    go.drugbank.com/drugs/DB18916
    Investigational

    Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection

    Synonyms: Immunoglobulin g1 (434-leucine,440-serine), anti-(human immunodeficiency virus 1 envelope protein gp120env) (human monoclonal 8c11-62a12 .gamma.1-chain), disulfide with human monoclonal 8c11-62a12 .kappa
  6. Drug

    Dilpacimab

    go.drugbank.com/drugs/DB16140
    Investigational

    Dilpacimab is under investigation in clinical trial NCT03368859 (A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine

    Synonyms: Immunoglobulin, anti-(notch ligand dll4/vascular endothelial growth factor) (synthetic human pr-1283233 heavy chain), disulfide with synthetic human pr-1283233 light chain, dimer
  7. Drug

    Zilovertamab

    go.drugbank.com/drugs/DB18403
    Investigational

    Synonyms: Immunoglobulin g1, anti-(human receptor tyrosine kinase ror-1) (human-mus musculus monoclonal uc-961 .gamma.1-chain), disulfide with human-mus musculus monoclonal uc-961 .kappa.-chain, dimerCategories: Immunoglobulins
  8. Drug

    Tagitanlimab

    go.drugbank.com/drugs/DB18221
    Investigational

    Synonyms: Immunoglobulin g1 (237-alanine,238-alanine,240-alanine), anti-(human programmed death-ligand 1) (human monoclonal kla167 .gamma.1-chain), disulfide with human monoclonal kla167 .kappa.-chain, dimer
  9. Drug

    Gatipotuzumab

    go.drugbank.com/drugs/DB18861
    Investigational

    Gatipotuzumab is under investigation in clinical trial NCT01899599 (Pankomab-gex™ Versus Placebo as Maintenance Therapy in Advanced Ovarian Cancer).

    Synonyms: Immunoglobulin g1, anti-(mucin muc1) (human-mus musculus monoclonal pankomab-gex heavy chain), disulfide with human-mus musculus monoclonal pankomab-gex light chain, dimer
  10. Drug

    Enapotamab vedotin

    go.drugbank.com/drugs/DB16156
    Investigational

    Enapotamab vedotin is under investigation in clinical trial NCT02988817 (Enapotamab Vedotin (Humax-axl-adc) Safety Study in Patients With Solid Tumors).

    Synonyms: Immunoglobulin g1, anti-(human growth factor receptor axl)(human humax-axl .gamma.1-chain), disulfide with human humax-axl .kappa.-chain, dimer tetrakis(thioether) with vedotin, Humax axl adc