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Colestipol
go.drugbank.com/drugs/DB00375ApprovedL6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is
Categories: Compounds used in a research, industrial, or household settingSynonyms: Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxiraneFerric sulfate
go.drugbank.com/drugs/DB11171ApprovedFerric sulfate has the molecular formula of Fe2SO4, and it is a dark brown or yellow chemical agent with acidic properties. It is produced by the reaction of sulfuric acid and an oxidizing agent. … [A32355, A32356] By the FDA, ferric sulfate is a direct food substance affirmed in the GRAS category (Generally Recognized As Safe).[L2003]
Rosoxacin
go.drugbank.com/drugs/DB00817ApprovedRosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. … Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered drug, which avoids all complications of parenteral administration seen with penicillin,
Synonyms: 1-ethyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acidCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP1A2 InhibitorsSacituzumab govitecan
go.drugbank.com/drugs/DB12893ApprovedInvestigational[A193671] One such ADC is sacituzumab govitecan, which combines a humanized anti-trophoblast cell-surface antigen 2 (TROP-2) antibody with the topoisomerase I inhibitor SN-38. … As a targeted cytotoxic agent, it is hoped to provide similar efficacy with reduced adverse effects.
Categories: Trop-2-Directed Monoclonal AntibodiesProducts: TRODELVY®, TRODELVY 200 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADETHuman thrombin
go.drugbank.com/drugs/DB11571ApprovedInvestigationalHuman thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting. … Thrombin is a highly specific serine protease encoded by the F2 gene that transforms soluble fibrinogen into insoluble fibrin.
Mixtures: EVICEL® SELLANTE DE FIBRINA HUMANAProducts: THROMBIRAAS1000 UIEthiodized oil
go.drugbank.com/drugs/DB00965ApprovedInvestigationalEthiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil. … And although these esters are primarily as ethyl monoiodostearate and ethyl diiodostearate, the actual, specific structure is unknown.
Categories: X-Ray Contrast Activity, X-Ray Contrast Media, IodinatedProducts: LIPIODOL ® ULTRA-FLUIDE, LİPİODUL ULTRA-FLUİD 480 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ , 5 MLBrimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigational[A178951] It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. … Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996.
Mixtures: NEFRIDAXEM B+D, Brimonidine Tartrate 0.25% / Ivermectin 1% / Metronidazole 1% / Niacinamide 4%Categories: Heterocyclic Compounds, 2-Ring, Adrenergic alpha-2 Receptor AgonistsTriclocarban
go.drugbank.com/drugs/DB11155ApprovedIt is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products. … Triclocarban, with the chemical formula C13H9Cl3N2O [L2675] is an antibacterial agent that is particularly effective against Gram-positive bacteria such as *Staphylococcus aureus*.
Synonyms: 1-(3',4'-dichlorophenyl)-3-(4'-chlorophenyl)urea, N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)ureaProducts: NEXT 1 Anti-bacterial, Next 1 Anti-Bacterial SportPerfluorohexyloctane
go.drugbank.com/drugs/DB17823ApprovedInvestigationalPerfluorohexyloctane is a semifluorinated alkane that contains six perfluorinated carbon atoms and eight hydrogenated carbon atoms.[L46491] It is an inert, slightly amphiphilic compound. … [A259746] Because it is a completely non-aqueous liquid, microbial growth is not possible; therefore, its drug products do not need to be combined with any preservative.
Synonyms: 1-(perfluorohexyl)octaneFinerenone
go.drugbank.com/drugs/DB16165ApprovedInvestigationalFinerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart … [A236544] So far, finerenone is the only nonsteroidal mineralocorticoid receptor antagonist to be FDA approved.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 Substrates