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Dostarlimab
go.drugbank.com/drugs/DB15627ApprovedInvestigational, including those of the skin, lung, kidneys, and liver. … [A234379] Agents acting on the PD-1 pathway, such as [nivolumab] and [pembrolizumab], facilitate endogenous immune-mediated anti-tumor activity and may therefore be used to treat a wide variety of cancers
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: Immunoglobulin G4, anti-programmed cell death protein 1 (PDCD1) (humanized clone ABT1 gamma4-chain), disulfide with humanized clone ABT1 kappa-chain, dimerTavokinogene telseplasmid
go.drugbank.com/drugs/DB17301InvestigationalTavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.
Synonyms: Dna plasmid containing genes coding for the human interleukin 12 (il-12) p35 and p40 subunits that are separated by an internal ribosomal entry site (ires) and under the control of a single cytomegalovirusLawsonia inermis leaf
go.drugbank.com/drugs/DB14313InvestigationalIt is not an approved drug.
Synonyms: Plants and Plant Parts, Henna Lawsonia InermisDepemokimab
go.drugbank.com/drugs/DB18846ApprovedInvestigationalaged 12 years and older. … [A275338] Approved by the FDA on December 16, 2025, depemokimab is indicated as an add-on maintenance treatment for severe asthma characterized by an eosinophilic phenotype in adult and paediatric patients
Synonyms: Immunoglobulin g1, anti-(human interleukin 5) (human-mus musculus monoclonal gsk3511294 .gamma.1-chain), disulfide with human-mus musculus monoclonal gsk3511294 .kappa.-chain, dimerCategories: Amino Acids, Peptides, and ProteinsAOC-1020
go.drugbank.com/drugs/DB18621InvestigationalAOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded
Synonyms: An antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotideZolbetuximab
go.drugbank.com/drugs/DB15118ApprovedInvestigational[A264723] Zolbetuximab was approved by the FDA in October 2024 for use in patients with HER2 negative, CLDN18.2-positive gastric and GEJ adenocarcinomas.[L51943,L51923] … Zolbetuximab (previously claudiximab)[A264748] is a chimeric cytolytic antibody comprising variable regions derived from mouse anti-human claudin-18 isoform 2 monoclonal antibody and constant regions derived
Synonyms: immunoglobulin G1, anti-(human Claudin-18.2) (human-mus musculus monoclonal IMAB362 heavy chain), disulfide with human-mus musculus monoclonal IMAB362 .kappa.-chain, dimerCategories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsAD-214
go.drugbank.com/drugs/DB18412InvestigationalSynonyms: Fc-fusion protein comprised of an anti-CXCR4 i-body tethered at its C-terminus to constant domains 2 and 3 of the Fc region of a mutated human IgG1Lym-1-I-131
go.drugbank.com/drugs/DB17445ExperimentalLym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant lymphocytes.
Synonyms: Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphomaApitegromab
go.drugbank.com/drugs/DB16096ApprovedInvestigational[L64184] It binds selectively to promyostatin and latent myostatin — the proforms of myostatin — and inhibits the activation of myostatin, thereby blocking myostatin signaling. … who are currently receiving an SMN2-targeted treatment.
Synonyms: Immunoglobulin g4 (234-proline), anti-(human progrowth differentiation factor 8) (human monoclonal srk-015 .gamma.4-chain), disulfide with human monoclonal srk-015 .lambda.-chain, dimerCategories: Amino Acids, Peptides, and Proteins