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Methyclothiazide
go.drugbank.com/drugs/DB00232ApprovedWithdrawnA thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)
Categories: combinations of sulfonamidesAnethole trithione
go.drugbank.com/drugs/DB13853Approvedfor many of these aforementioned functions at this time and is only used in limited regions around the world. … Anethole trithione (ATT) appears to have a broad range of unique functions, from increasing salivary secretion to help treat xerostomia [A27165, A32618, A32620, A32621], to demonstrating an ability to
Diamorphine
go.drugbank.com/drugs/DB01452ApprovedIllicitAs heroin, it is illegal to manufacture, possess, or sell in the United States and the UK. However, under the name diamorphine, heroin is a legal prescription drug in the United Kingdom. … Diamorphine (heroin) is a narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S.
Categories: Heterocyclic Compounds with 4 or More RingsSynonyms: O,O'-DiacetylmorphineEdetic acid
go.drugbank.com/drugs/DB00974ApprovedInvestigationalVet approvedA chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Categories: Compounds used in a research, industrial, or household settingEthinylestradiol
go.drugbank.com/drugs/DB00977ApprovedInvestigational[A191107] These properties were achieved by the substitution of an ethinyl group at carbon 17 of [estradiol].[A191107] Ethinylestradiol soon replaced [mestranol] in contraceptive pills. … [A191107] Ethinylestradiol was granted FDA approval on 25 June 1943.[L11884]
Mixtures: OC - 35, O - ZETTECategories: Sex Hormones and Modulators of the Genital SystemSparsentan
go.drugbank.com/drugs/DB12548ApprovedInvestigationalSparsentan is a dual antagonist of the endothelin type A receptor (ET<sub>A</sub>R) and the angiotensin II (Ang II) type 1 receptor (AT<sub>1</sub>R) with a similar affinity for both (9.3 nM for ET<sub … [A257330] In February 2023, the use of sparsentan to reduce proteinuria in adults with primary immunoglobulin A nephropathy (IgAN) at risk of rapid disease progression was approved by the FDA under
Categories: Agents Acting on the Renin-Angiotensin System, Dual Endothelin Type A Receptor/Ang II Subtype 1 Receptor Antagonist (DEARA)Trichlormethiazide
go.drugbank.com/drugs/DB01021ApprovedVet approvedA thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
Categories: combinations of sulfonamidesInternational brands: Diu-HydrinBremelanotide
go.drugbank.com/drugs/DB11653Approved[A179686] The mechanism by which bremelanotide's action on receptors translates to a clinical effect is still unknown. … [A179689] Bremelanotide was granted FDA approval on 21 June 2019.[L9635]
Zafirlukast
go.drugbank.com/drugs/DB00549ApprovedZafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. … It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once daily.
Synonyms: cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methylindole-5-carbamate, 4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamideMetrizamide
go.drugbank.com/drugs/DB01578ExperimentalMetrizamide is a solute for density gradient centrifugation offering higher maximum solution density without the problems of increased viscosity. … It is also used as a resorbable, non-ionic contrast medium.
Categories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of Chemicals