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Xylometazoline
go.drugbank.com/drugs/DB06694ApprovedXylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity.
Mixtures: Ophtrivin A Ophthalmic Dps, nasic - Nasenspray für Kinder 5 mg/500 mgCategories: Adrenergic alpha-1 Receptor Agonists, Heterocyclic Compounds, 1-RingGentian violet cation
go.drugbank.com/drugs/DB00406ApprovedA dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
Mixtures: Kerr 100 Triple Dye Dispos-ASynonyms: Crystal violet(1+), Gentian violet(1+)Favipiravir
go.drugbank.com/drugs/DB12466ApprovedInvestigational[A191688,A191772,A191775] Not only does favipiravir inhibit replication of influenza A and B, but the drug has shown promise in the treatment of avian influenza, and may be an alternative option for … Discovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2C8 InhibitorsProducts: L-VIR, KOVİPİR 200 MG FİLM KAPLI TABLET, 40 ADETAbiprubart
go.drugbank.com/drugs/DB19333InvestigationalAbiprubart is being evaluated for its efficacy and safety in participants with Sjögren's Disease in clinical trial NCT06531395
Synonyms: Gamma4 heavy chain humanized (1-441) [VH (Homo sapiens IGHV1-3*01 (83.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1, (115-212), hinge 1-12 S10>P (222) (213-224), CH2 LNicotine
go.drugbank.com/drugs/DB00184ApprovedInvestigationalIt is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 SubstratesSynonyms: L(−)-nicotine, (S)-3-(1-methylpyrrolidin-2-yl)pyridineFlumazenil
go.drugbank.com/drugs/DB01205ApprovedInvestigationalFumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingProducts: ANESED-R 1 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, ANTİZEPİN 1 MG/10 ML İ.V. ENJEKSİYONLUK ÇÖZELTİ, 5 ADETBisoprolol
go.drugbank.com/drugs/DB00612ApprovedInvestigational[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. … Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.
Mixtures: CONCOR ® AM 5 MG / 10 MG, CONCOR ® AM 5 MG / 10 MGCategories: P-glycoprotein inhibitors, P-glycoprotein substratesImipramine
go.drugbank.com/drugs/DB00458ApprovedInvestigationalImipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. … In depressed individuals, imipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine, 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepineNaloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approved[L33734] Kits commonly include the supplies necessary to treat an overdose in a non-medical setting such as alcohol swabs, syringes, a rescue breathing mask, and instructions for use. … [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors.
Mixtures: TARGIN ® 20 MG / 10 MG TABLETAS DE LIBERACIÓN PROLONGADA, TARGIN ® 20 MG / 10 MG TABLETAS DE LIBERACIÓN PROLONGADACategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPyrazinamide
go.drugbank.com/drugs/DB00339ApprovedInvestigationalA pyrazine that is used therapeutically as an antitubercular agent.
Mixtures: RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MG, RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MGCategories: Heterocyclic Compounds, 1-Ring