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Maprotiline
go.drugbank.com/drugs/DB00934ApprovedIt differs from TCAs in that it does not appear to block serotonin reuptake. … Maprotiline is effective at reducing symptoms of anxiety associated with depression.
Products: Ludiomil Tab 10mg, Novo-maprotiline - Tab 10mgTolterodine
go.drugbank.com/drugs/DB01036ApprovedInvestigationalTolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Products: DETRUSITOL 1MG, TOLTERODIN PFI 1MGEbastine
go.drugbank.com/drugs/DB11742ApprovedInvestigationalWithdrawnEbastine has been investigated for the treatment of Urticaria.
Products: EBASTEL 10MG, EBASTIN ARISTO 10MGMirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigationalIt may improve the symptoms of neurological disorders, reverse weight loss caused by medical conditions, improve sleep, and prevent nausea and vomiting after surgery.[A177811] … [T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy.
Products: MIRTAZAPIN - CT 15MG, MIRTAZAPIN HEU 15MG NETInositol
go.drugbank.com/drugs/DB13178ApprovedInvestigationalWithdrawnIt is considered a pseudovitamin as it is a molecule that does not qualify to be an essential vitamin because even though its presence is vital in the body, a deficiency in this molecule does not translate … [L1113] By the FDA, inositol is considered in the list of specific substances affirmed as generally recognized as safe (GRAS).[L2561]
Mixtures: B Compound 50mg Tab, Revitex Ampoules Et ComprimesProducts: Inositol Tab 250mg, Inositol 250mg - TabRisperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigational[L12885] It is one of the most widely used SGAs. [Paliperidone], another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). … [L12885] Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors, and carries lesser activity at several off-targets
Products: RISPERIDON HEU 1MG NET, RISPERIDON - CT 1MG FILMTAValsartan
go.drugbank.com/drugs/DB00177ApprovedInvestigationalThe angiotensin II receptor blocker (ARB) family of drugs unique in that it blocks all angiotensin II activity, regardless of where or how it was synthesized. … [A174124,A173869] Valsartan was initially approved in 1996 in Europe for the treatment of hypertension in adults. Shortly after, in 1997, this drug was approved in the United States.
Mixtures: Exforge HCT Tablet 10mg/160mg/25mg, Amlodipin/Valsartan/HCT +pharma 10mg/160mg/25mg FilmtablettenProducts: PMS-valsartan, VALSARTAN CT 80MGTadalafil
go.drugbank.com/drugs/DB00820ApprovedInvestigational[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. … of PAH.
Mixtures: OPSYNVI (10mg macitentan/ 20mg tadalafil) film-coated tablets, OPSYNVI (10mg macitentan/ 40mg tadalafil) film-coated tabletsProducts: TADACIP 10MG, DURAX FAST VSD 10MGFenofibrate
go.drugbank.com/drugs/DB01039ApprovedInvestigational[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.[L8585]
Mixtures: SIMITRI®145/20MG, PRAVAFEN HARD CAPSULES 40mg/160mgProducts: CHOLIB FILM-COATED TABLET 145MG/20MG, Lipidil Cap 100mgBuprenorphine
go.drugbank.com/drugs/DB00921ApprovedIllicitInvestigationalVet approved[A186283,A186292] It is also commonly used as an alternative to [methadone] for the treatment of severe opioid addiction. … Buprenorphine may also be a preferred agent over [methadone] (which is also commonly used to treat severe pain and opioid use disorder), as it has less effect on Qtc interval prolongation,[A186271,A186274
Mixtures: BUPREN 8MG/2MG SUBLINGUAL TABLET, SUBOXONE SUBLINGUAL FILM 8MG/2MGProducts: NORSPAN 10UG/H 10MG, TRANSTEC 70 UG/H 40MG