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Acipimox
go.drugbank.com/drugs/DB09055ApprovedInvestigationalFlushing can be reduced by taking aspirin 20-30 min before taking Acipimox. High doses can cause disorders of liver function, impair glucose tolerance and precipitate gout. … Acipimox is a niacin derivative used as a hypolipidemic agent.
Categories: Heterocyclic Compounds, 1-RingMitomycin
go.drugbank.com/drugs/DB00305ApprovedInvestigational[A193419] Mitomycin's cross-linking activity has resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper … Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of _Streptomyces caespitosus_.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: Mito-C, Mitocin-CKER-047
go.drugbank.com/drugs/DB19111InvestigationalKER-047 is under investigation in clinical trial NCT05927012 (A Study to Evaluate the Safety and Preliminary Efficacy of a Response-guided Dose Titration of KER-047 in the Treatment of Functional IDA (
Synonyms: QUINOLINE, 7-FLUORO-6-METHOXY-4-(6-(4-(4-METHYL-1-PIPERAZINYL)-1-PIPERIDINYL)PYRAZOLO(1,5-A)PYRIMIDIN-3-YL)-Omidenepag isopropyl
go.drugbank.com/drugs/DB15071ApprovedThe use of an EP2 receptor agonist such as omidenepag represents an alternative in these scenarios. Omidenepag IOP-lowering effect is comparable to the one observed with [latanoprost]. … Omidenepag isopropyl is a topical ocular hypotensive agent used to reduce intraocular pressure (IOP) in patients with glaucoma and ocular hypertension.
Synonyms: isopropyl N-(6-(((4-(1H-pyrazol-1-yl)benzyl)(3-pyridinylsulfonyl)amino)methyl)-2-pyridinyl)glycinateCategories: Heterocyclic Compounds, 1-Ring, Receptors, Prostaglandin E, EP2 Subtype, agonistsDuvakitug
go.drugbank.com/drugs/DB19444InvestigationalDuvakitug is under investigation in clinical trial NCT05668013 (A Study to Evaluate the Long-term Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease).
Synonyms: Immunoglobulin G1 [de-449-lysine], anti-(human tumor necrosis factor superfamily protein TNFSF15) (human monoclonal TEV-48574 γ1-chain), disulfide with human monoclonal TEV-48574 λ-chain, dimer, gamma1 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV1-8*01 (92.9%) -(IGHD) -IGHJ4*01 (92.9%),CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119)-Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, CH3Tiopronin
go.drugbank.com/drugs/DB06823ApprovedTiopronin may also be used to bind metal nanoparticles in Wilson's disease, which is an overload of copper in the body. … As cystinuria is a relatively rare disease, tiopronin is classified as an orphan drug and is not patented in the United States.
Categories: N-substituted GlycinesInternational brands: Kai NaDaratumumab
go.drugbank.com/drugs/DB09331ApprovedInvestigationalDaratumumab is an immunoglobulin G1 kappa monoclonal antibody developed by Janssen and Genmab. … [A7935] It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind.
Products: DARZALEX® SC 120 MG/ML SOLUCIÓN INYECTABLE, DARZALEX 100 MG/5 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRESER-287
go.drugbank.com/drugs/DB18204InvestigationalSER-287 comprises healthy microbiome-derived Gram positive bacterial spores.
LTI-03
go.drugbank.com/drugs/DB18491InvestigationalLTI-03 is a caveolin-1 Scaffolding Domain 7-Mer
Synonyms: L-threonine, l-phenylalanyl-l-threonyl-l-threonyl-l-phenylalanyl-l-threonyl-l-valyl-Bempedoic acid
go.drugbank.com/drugs/DB11936ApprovedInvestigationalCaused by genetic mutations or lifestyle factors, hypercholesterolemia can significantly reduce quality of life and increase the risk of mortality from cardiovascular disease. … High levels of LDL cholesterol (LDL-C) are a major risk factor for cardiovascular events.