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Zuclopenthixol
go.drugbank.com/drugs/DB01624ApprovedInvestigationalZuclopenthixol was approved for use in Canada in 2011, but is not approved for use in the United States. … Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent.
Escitalopram
go.drugbank.com/drugs/DB01175ApprovedInvestigational[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with some evidence suggesting … [A39738,A185819] Amongst SSRIs, escitalopram exerts the highest degree of selectivity for the serotonin transporter (SERT) relative to other off-targets which may explain its lower rates of adverse effects
Categories: Antidepressive Agents Indicated for DepressionMethimazole
go.drugbank.com/drugs/DB00763ApprovedInvestigational[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949[A184502] and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive … options such as surgery or radioactive iodine therapy are inappropriate.
Lorlatinib
go.drugbank.com/drugs/DB12130ApprovedInvestigationalLorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer[L39905] which was first approved by the US FDA in November of 2018 … It was subsequently approved by the EMA in 2019 for the treatment of select patients with previously treated advanced ALK-positive non-small cell lung cancer, followed by an expanded approval in 2022 to
Lesinurad
go.drugbank.com/drugs/DB11560ApprovedWithdrawnMarketed as the product Zurampic, it is indicated for use in combination with a xanthine oxidase inhibitor for the treatment of hyperuricemia associated with gout in patients who have not achieved target … Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout.
Pipradrol
go.drugbank.com/drugs/DB11584ApprovedWithdrawnInterestingly, this drug has been studied for bactericidal properties, however, is not currently, used for this purpose [A32725]. … Experimentation with the drug and its derivatives for recreational purposes has led to many cases of acute toxicity and has been linked to three fatalities.
Categories: Psychostimulants, Agents Used for ADHD and NootropicsRubella virus vaccine
go.drugbank.com/drugs/DB10317ApprovedInvestigationalRubella virus vaccine is a live attenuated virus vaccine for active immunization against rubella (German measles) that is subcutaneously administered.
Mixtures: Sterile Diluent for M-M-R IICategories: Antiinfectives for Systemic UseCeliprolol
go.drugbank.com/drugs/DB04846ApprovedInvestigationalWithdrawnCeliprolol is not approved for use by the FDA in the treatment of vascular Ehlers–Danlos syndrome. … Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.
Peramivir
go.drugbank.com/drugs/DB06614ApprovedInvestigationalfor no more than two days. … The development of peramivir has been supported by the US Department of Health and Human Services as part of the government's effort to prepare for a flu pandemic.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseGlatiramer
go.drugbank.com/drugs/DB05259ApprovedInvestigational[A248870] Along with [human interferon beta], [teriflunomide], and [dimethyl fumarate], glatiramer acetate is a first-line drug for patients with MS.