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Daclatasvir
go.drugbank.com/drugs/DB09102ApprovedInvestigationalWithdrawnThe therapy is intended to cure or achieve a sustained virologic response (SVR12), after 12 weeks of daily therapy. … Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection.
Categories: Heterocyclic Compounds, 1-Ring, Antivirals for Systemic UseProducts: DASVIR 30 (DACLATASVIR TABLETS 30 MG), DASVIR 60 (DACLATASVIR TABLETS 60 MG)Picosulfuric acid
go.drugbank.com/drugs/DB09268ApprovedInvestigationalSodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels before colonoscopy or surgery. … The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian market in 2005 and has been used in European countries for many years.[A33322]
Mixtures: PICOPREP 10 MG / 3,5 G /12 G ORAL ÇÖZELTI IÇIN TOZ, 2 SAŞE, AGAROL CON SABOR A FRAMBUESACategories: Heterocyclic Compounds, 1-Ring, Drugs for ConstipationAbatacept
go.drugbank.com/drugs/DB01281ApprovedInvestigationalAlthough approved for the treatment of rheumatoid arthritis, Repligen has entered a slightly different formulation of CTLA4-Ig into clinical trials (RG2077). … [L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each
Categories: Biologics for Rheumatoid Arthritis TreatmentProducts: ORENCIA® SOLUCION INYECTABLE PARA ADMINISTRACION SUBCUTÁNEA 125 MG/ML, ORENCIA 250 MG KON.PERFUZYONLUK COZ.ICIN TOZ ICEREN FLAKONCeftazidime
go.drugbank.com/drugs/DB00438ApprovedInvestigational[L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone or in combination with the non-β-lactam β-lactamase inhibitor [avibactam] to treat a variety of … Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding
Mixtures: CEFAZIME FOR INJECTION 1 g/vial, ZAVİCEFTA 2 G/0.5 G İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 10 ADETCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseEsketamine
go.drugbank.com/drugs/DB11823ApprovedInvestigationalThe intranasal route of administration for this drug allows for easy administration and a fast onset of action, which sets it apart from many other antidepressant agents that may take several weeks to … Ketamine is a mixture of two enantiomers (mirror image molecules). This is the first time that the FDA has approved esketamine for any use. The FDA approved ketamine (Ketalar) in 1970.
Categories: Antidepressive Agents Indicated for DepressionSynonyms: L-ketamineDulaglutide
go.drugbank.com/drugs/DB09045ApprovedInvestigationalDulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct … [A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular
Categories: Glucagon-like peptide-1 (GLP-1) analogues, GLP-1 AgonistsProducts: TRULICITY® 1.5 MG/0.5 ML, TRULICITY® 0.75 MG/0.5 MLDe Novo Triacylglycerol Biosynthesis TG(10:0/10:0/a-21:0)
smpdb.ca/view/SMP0031704MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...
De Novo Triacylglycerol Biosynthesis TG(10:0/10:0/i-13:0)
smpdb.ca/view/SMP0031707MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...
Cardiolipin Biosynthesis CL(10:0/10:0/11:0/a-15:0)
smpdb.ca/view/SMP0175325MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Cardiolipin Biosynthesis CL(10:0/10:0/11:0/a-25:0)
smpdb.ca/view/SMP0175328MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...