Search

Displaying results 1651 - 1660 of 10000 in total
  1. Drug

    Fialuridine

    go.drugbank.com/drugs/DB15427
    Investigational

    Fialuridine is under investigation in clinical trial NCT01337466 (Biodistribution and Dosimetry Evaluation of [124I]FIAU).

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Rupitasertib

    go.drugbank.com/drugs/DB15431
    Investigational

    M-2698 is under investigation in clinical trial NCT01971515 (First-in-Human Dose Escalation Trial in Subjects With Advanced Malignancies).

    Synonyms: M-2698
  3. Drug

    Pinatuzumab vedotin

    go.drugbank.com/drugs/DB15432
    Investigational

    Obinutuzumab in Participants With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)). … Pinatuzumab vedotin is under investigation in clinical trial NCT01691898 (A Study of Pinatuzumab Vedotin (DCDT2980S) Combined With Rituximab or Polatuzumab Vedotin (DCDS4501A) Combined With Rituximab or

  4. Drug

    AVI-7537

    go.drugbank.com/drugs/DB15433
    Investigational

    [L46207] AVI-7537 is under investigation in clinical trial NCT01593072 (A Study to Assess the Safety, Tolerability and Pharmacokinetics of AVI-7537 in Healthy Adult Volunteers).

    Synonyms: 5'-GCCATGGTTTTTTCTCAGG-3'
  5. Drug

    Mosunetuzumab

    go.drugbank.com/drugs/DB15434
    ApprovedInvestigational

    [L42245] In June 2022, the European Medicines Agency approved mosunetuzumab for the treatment of adult patients with relapsed or refractory (R/R) FL who have received at least two prior systemic therapies … [L42230] It can recognize and bind two different targets simultaneously, CD20 on cancer B-cells and CD3 on T-cells, allowing it to redirect T-cell cytotoxic activity to cancer cells.

  6. Drug

    Rocacetrapib

    go.drugbank.com/drugs/DB15437
    Investigational

    Rocacetrapib is under investigation in clinical trial NCT02156544 (Study to Investigate the Safety/Tolerability and Pharmacokinetics/Pharmacodynamics of CKD-519).

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    SOBI-003

    go.drugbank.com/drugs/DB15451
    Investigational

    SOBI-003 is a chemically modified variant of a recombinant human sulfamidase. … It is under investigation in clinical trial NCT03811028 (A Study to Assess the Safety, Tolerability, and Efficacy of Long-term SOBI003 Treatment in Pediatric MPS IIIA Patients).

  8. Drug

    Vericiguat

    go.drugbank.com/drugs/DB15456
    ApprovedInvestigational

    [A227458,A227488] Cyclic GMP acts as a second messenger, activating a number of downstream signaling cascades that elicit a broad variety of effects, and these diverse cellular effects have implicated … [A227458] As a direct stimulator of sGC, vericiguat mitigates the need for a functional NO-sGC-cGMP axis and thereby helps to prevent the myocardial and vascular dysfunction associated with decreased sGC

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingProducts: VERQUVO® 5MG TABLETAS RECUBIERTAS, VERQUVO® 10MG TABLETAS RECUBIERTAS
  9. Drug

    Snubh-nm-333 F-18

    go.drugbank.com/drugs/DB15457
    Experimental

    Snubh-nm-333 F-18 is under investigation in clinical trial NCT02149017 (Phase 1 and Phase 2 Clinical Trials of SNUBH-NM-333(18F)).

  10. Drug

    Yersinia pestis 195/p antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB15461
    Investigational

    Yersinia pestis 195/p antigen (formaldehyde inactivated) is under investigation in clinical trial NCT02596308 (Immunogenicity and Safety of Subunit Plague Vaccine).

    Categories: Complex MixturesSynonyms: Yersinia pestis 195/p antigen (formaldehyde inactivated)