Search

Displaying results 161 - 170 of 10000 in total
  1. Drug

    5'-Guanylylmethylenebisphosphonate

    go.drugbank.com/drugs/DB03725
    Experimental

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 5'-Guanosyl-methylene-triphosphate, 5'-Guanylylmethylenebisphosphonate
  2. Drug

    Ethynodiol diacetate

    go.drugbank.com/drugs/DB00823
    Approved

    A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. … Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug

    Mixtures: Kelnor 1/50, Valtya 1/50Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  3. Drug

    Lotilaner

    go.drugbank.com/drugs/DB17992
    ApprovedInvestigationalVet approved

    The active ingredient found in drug products of lotilaner is the S-enantiomer. … Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-thiophenecarboxamide, 5-((5s)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl)-3-methyl-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-, 3-methyi-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-5-((55)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)thiophene-2-carboxamide
  4. Drug

    Glipizide

    go.drugbank.com/drugs/DB01067
    ApprovedInvestigational

    According to the 2018 Clinical Practice Guidelines by Diabetes Canada, sulfonylurea drugs are considered a second-line glucose-lowering therapy following metformin. … Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus.

    Categories: Drugs Used in Diabetes, Cytochrome P-450 SubstratesSynonyms: N-{4-[β-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea, 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea
  5. Drug

    Edaravone

    go.drugbank.com/drugs/DB12243
    ApprovedInvestigational

    Edaravone is a free radical scavenger and neuroprotective agent with antioxidant properties.[A254257] It has three tautomers. … by the Committee for Medicinal Products for Human Use (CHMP) for a long-term study demonstrating the long-term efficacy and safety of edaravone.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingSynonyms: 1-phenyl-3-methyl-5-oxo-2-pyrazoline, 3-methyl-1-phenyl-5-pyrazolone
  6. Drug

    Olmesartan

    go.drugbank.com/drugs/DB00275
    ApprovedInvestigational

    In particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function. … Olmesartan is commonly used for the management of hypertension and Type 2 Diabetes-associated nephropathy, particularly in patients who are unable to tolerate ACE inhibitors.

    Mixtures: OLMETECANLO® 20 MG / 5 MG, NORMETEC (TABLETS 5 MG/20 MG)Categories: Angiotensin 2 Receptor Blocker, Agents Acting on the Renin-Angiotensin System
  7. Drug

    Sumatriptan

    go.drugbank.com/drugs/DB00669
    ApprovedInvestigational

    Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches. … [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines.

    Mixtures: TRASS® TABLETA RECUBIERTA, TRASS® TABLETA RECUBIERTACategories: Serotonin 5-HT1 Receptor Agonists, Selective Serotonin 5-HT1 Receptor Agonists
  8. Drug

    Gimeracil

    go.drugbank.com/drugs/DB09257
    ApprovedInvestigational

    The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic anti-metabolite drug that acts on rapidly dividing cancer cells. … It functions by reversibly and selectively blocking the enzyme dihydropyrimidine dehydrogenase (DPD), which is involved in the degradation of 5-FU [A31408].

    Mixtures: TS-ONE CAPSULE 25, TS-ONE CAPSULE 25Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Hexaminolevulinate

    go.drugbank.com/drugs/DB06261
    ApprovedInvestigational

    Hexaminolevulinate is manufactured under the brand Cysview® by Photocure ASA. In Europe, Hexaminolevulinate is marketed under the brand Hexvix®. … Karl Storz Photodynamic Diagnostic D-Light C (PDD) System for cystoscopic detection of non-muscle invasive papillary cancer of the bladder for patients suspected or known to have lesion(s) on the basis

    Synonyms: Hexyl 5-amino-4-oxopentanoate hydrochloride, Hexyl(5-amino-4-oxopentanoat)-hydrochloridProducts: Hexvix 85 mg Pulver und Lösungsmittel zur Herstellung einer Lösung zur intravesikalen Anwendung
  10. Drug

    Chlorothymol

    go.drugbank.com/drugs/DB19375
    Approved

    Chlorotymol is a [Thymol] derivative.

    Synonyms: 4-chlor-2-isopropyl-5-methylphenol, 4-chloro-5-methyl-2-(1-methylethyl)phenol