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Displaying results 1721 - 1730 of 2816 in total
  1. Drug

    Tauromustine

    go.drugbank.com/drugs/DB19978
    Experimental

    Tauromustine is a small molecule drug. The usage of the INN stem '-mustine' in the name indicates that Tauromustine is a antineoplastic, alkylating agent, (β-chloroethyl) amine derivative. Tauromustine has a monoisotopic molecular weight...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  2. Drug

    Azamulin

    go.drugbank.com/drugs/DB20304
    Experimental

    Azamulin is a small molecule drug. Azamulin has a monoisotopic molecular weight of 478.26 Da.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 Substrates
  3. Drug

    Cloperidone

    go.drugbank.com/drugs/DB20327
    Experimental

    Cloperidone is a small molecule drug. Cloperidone has a monoisotopic molecular weight of 398.15 Da.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Inhibitors
  4. Drug

    Mofarotene

    go.drugbank.com/drugs/DB20333
    Experimental

    Mofarotene is a small molecule drug. The usage of the INN stem '-arotene' in the name indicates that Mofarotene is a arotinoid derivative. Mofarotene has a monoisotopic molecular weight of 433.3 Da.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    Burapitant

    go.drugbank.com/drugs/DB20607
    Experimental

    The usage of the INN stem '-pitant' in the name indicates that Burapitant is a neurokinin NK1​ (substance P) receptor antagonist. Burapitant has a monoisotopic molecular weight of 681.2 Da.

  6. Drug

    Ethyl biscoumacetate

    go.drugbank.com/drugs/DB08794
    ApprovedWithdrawn

    Ethyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  7. Drug

    Bopindolol

    go.drugbank.com/drugs/DB08807
    Experimental

    Bopindolol (INN) is an ester prodrug for the beta blocker pindolol.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  8. Drug

    Lurasidone

    go.drugbank.com/drugs/DB08815
    ApprovedInvestigational

    Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the t...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Ivacaftor

    go.drugbank.com/drugs/DB08820
    ApprovedInvestigational

    Ivacaftor (also known as Kalydeco or VX-770) is a drug used for the management of Cystic Fibrosis (CF). It is manufactured and distributed by Vertex Pharmaceuticals. It was approved by the Food and Drug Administration on January 31, 2012...

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  10. Drug

    Deferiprone

    go.drugbank.com/drugs/DB08826
    ApprovedInvestigational

    Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Substrates