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RG2417
go.drugbank.com/drugs/DB05055InvestigationalRecent reports indicate that certain genes that encode for mitochondrial proteins are significantly down regulated in the brains of bipolar patients. … RG2417 is a proprietary formulation of uridine, a biological compound essential for the synthesis of DNA and RNA, the basic hereditary material found in all cells, and numerous other factors essential
Trichloroethylene
go.drugbank.com/drugs/DB13323ApprovedIt has been sold under a variety of trade names including Trimar and Trilene and used as a volatile anesthetic and as an inhaled obstetrical analgesic. … Environmental exposure, particularly groundwater and drinking water contamination from industrial discharge, is a major concern for human health and has been the subject of numerous incidents and lawsuits
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 InhibitorsSynonyms: 1,1-dichloro-2-chloroethyleneCeliprolol
go.drugbank.com/drugs/DB04846ApprovedInvestigationalWithdrawnIt is simultaneously a selective β1 receptor antagonist, a β2 receptor partial agonist and a weak α2 receptor antagonist. … In 2010 a clinical trial has suggested a use for this medication in the prevention of vascular complications of a rare inherited disease called vascular Ehlers–Danlos syndrome.
Categories: Adrenergic beta-2 Receptor Agonists, Adrenergic beta-3 Receptor AgonistsSynonyms: RS)-N'-{3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-N,N-diethylureaHuman Retinoid X Receptors (RXRs)
go.drugbank.com/bio_entities/BE0010096TargetHumansReceptor for retinoic acid. … Receptor for retinoic acid.
Polypeptides: Retinoic acid receptor RXR-alpha, Retinoic acid receptor RXR-betaSynonyms: Retinoid X receptor alpha, Retinoid X receptor betaPeroxisome proliferator-activated receptors
go.drugbank.com/bio_entities/BE0010120TargetHumans and other mammalsLigand-binding results in a conformational change in the receptor, promoting dissociation of repressors and recruitment of coactivators, and subsequent activation of target gene expression (PubMed:16150867 … Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand
Polypeptides: Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor deltaSynonyms: Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member 1Darunavir
go.drugbank.com/drugs/DB01264ApprovedInvestigationalDarunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of HIV-1 infection. … [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19, due to in vitro evidence supporting its ability to combat this infection.
Mixtures: FURTHAS®R TABLETAS RECUBIERTAS, PREZCOBIX® TABLETAS RECUBIERTASCategories: P-glycoprotein inducers, P-glycoprotein inhibitorsStanozolol
go.drugbank.com/drugs/DB06718ApprovedVet approvedStanozolol is a synthetic anabolic steroid with therapeutic uses in treating hereditary angioedema. … Stanozolol is derived from testosterone, and has been abused by several high profile professional athletes.
Products: อโซลอล 5 มก.Prostaglandin E2 Receptors
go.drugbank.com/bio_entities/BE0010100TargetHumansReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. … Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system.
Polypeptides: Prostaglandin E2 receptor EP1 subtype, Prostaglandin E2 receptor EP2 subtypeSynonyms: PGE receptor EP1 subtype, Prostanoid EP1 receptorCRx-119
go.drugbank.com/drugs/DB05688ExperimentalCRx-119 is a combination of a low dose of the steroid prednisolone, 3mg, and amoxapine. … CRx-119 is a novel synergistic combination drug candidate discovered using the CombinatoRx combination High Throughput Screening (cHTS(TM)) technology with potential therapeutic use in a broad range of
Piritramide
go.drugbank.com/drugs/DB12492ApprovedWithdrawnPiritramide has been investigated for the supportive care of Pain, Postoperative and Postoperative Nausea and Vomiting.
Categories: Heterocyclic Compounds, 1-Ring