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Viagenpumatucel-L
go.drugbank.com/drugs/DB16348InvestigationalViagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l (HS-110) in Patients With Non-small Cell Lung Cancer).
Synonyms: Gp96-igg1-fc fusion protein and hla-a1 expressing, irradiated ad-100 whole cell vaccineNendratareotide uzatansine
go.drugbank.com/drugs/DB18351InvestigationalNendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated to the cytotoxin mertansine.
Synonyms: Peptide-drug conjugate combining [(Tyr3,Cys8) octreotate amide] and N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl) maytansineTRK-001
go.drugbank.com/drugs/DB18577InvestigationalTRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Synonyms: Natural Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), Rapamycin and Transforming Growth Factor-betaCLL1-CD33 compound chimeric antigen receptor T cells
go.drugbank.com/drugs/DB18568InvestigationalSynonyms: Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33Telcagepant
go.drugbank.com/drugs/DB12228InvestigationalCGRP and its receptors are found in areas of the central and peripheral nervous system that are important for the transmission of migraine pain. … During migraine attacks, CGRP activates these receptors and facilitates the transmission of pain impulses.
Salts: Telcagepant potassiumFepixnebart
go.drugbank.com/drugs/DB19079InvestigationalFepixnebart is under investigation in clinical trial NCT04456686 (Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Osteoarthritis).
Synonyms: Ly3016859 (humanized monoclonal antibody to human tgf.alpha. and epiregulin), IMMUNOGLOBULIN G4 (226-PROLINE,232-ALANINE,233-ALANINE,DE-C-TERMINAL-LYSINE), ANTI-(HUMAN EPIREGULIN AND TRANSFORMING GROWTH FACTOR .ALPHA.)DT-DEC01
go.drugbank.com/drugs/DB19433ExperimentalDT-DEC01 is a novel Dystrophin Expressing Chimeric (DEC) cell therapy being investigated by Dystrogen Therapeutics Corporation.
Synonyms: Dystrophin Expressing Chimeric Cells derived from allogenic normal human myoblast and autologous DMD myoblast from Duchenne muscular dystrophy affected donorIncadronic acid
go.drugbank.com/drugs/DB06255ExperimentalAlong with being investigated to treat hypercalcemia of malignancy,[A202862] it has also been investigated in the treatment of myeloma, leukemia, and other cancers.
Salts: Disodium incadronate