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Displaying results 171 - 180 of 14198 in total
  1. Drug

    S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE

    go.drugbank.com/drugs/DB04720
    Experimental

    Synonyms: S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
  2. Drug

    S-Ethyl-N-Phenyl-Isothiourea

    go.drugbank.com/drugs/DB03707
    Experimental

    Synonyms: S-Ethyl-N-Phenyl-Isothiourea
  3. Drug

    N-Propargyl-1(S)-Aminoindan

    go.drugbank.com/drugs/DB03894
    Experimental

    Synonyms: N-Propargyl-1(S)-Aminoindan
  4. Drug

    (C8-S)-Hydantocidin 5'-phosphate

    go.drugbank.com/drugs/DB04460
    Experimental

    Synonyms: (C8-S)-Hydantocidin 5'-phosphate
  5. Drug

    Duloxetine

    go.drugbank.com/drugs/DB00476
    ApprovedInvestigational

    Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … [A178741] Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: (S)-duloxetine, (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine
  6. Drug

    Almitrine

    go.drugbank.com/drugs/DB01430
    Approved

    Almitrine is a respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. … It is also reported to have a potentially beneficial effect in treating the noctural oxygen desaturation without impairing the quality of sleep.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 2,4-Bis(allylamino)-6-(4-(bis(p-fluorophenyl)methyl)-1-piperazinyl)-s-triazine
  7. Drug

    Levofloxacin

    go.drugbank.com/drugs/DB01137
    ApprovedInvestigational

    Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. … [L11638] Levofloxacin, along with other quinolones such as [gatifloxacin] and [moxifloxacin], is a member of the third generation of fluoroquinolones, colloquially referred to as the "respiratory quinolones

    Categories: 4-Quinolones, MATE 1 InhibitorsSynonyms: (S)-Ofloxacin, Ofloxacin S-(-)-form
  8. Drug

    Rifabutin

    go.drugbank.com/drugs/DB00615
    ApprovedInvestigational

    A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.

    Categories: P-glycoprotein inducers, Cytochrome P-450 SubstratesSynonyms: 4-N-isobutylspiropiperidylrifamycin S, 4-Deoxo-3,4-(2-spiro(N-isobutyl-4-piperidyl)-2,5-dihydro-1H-imidazo)-rifamycin S
  9. Drug

    Darifenacin

    go.drugbank.com/drugs/DB00496
    ApprovedInvestigational

    This block reduces the urgency to urinate and so it should not be used in people with urinary retention. … Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsSynonyms: (S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-α,α-diphenyl-3-pyrrolidineacetamide
  10. Drug

    Altretamine

    go.drugbank.com/drugs/DB00488
    ApprovedWithdrawn

    An alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2,4,6-tris(dimethylamino)-s-triazine