Search
Thymidine
go.drugbank.com/drugs/DB04485ApprovedInvestigational[A274683] While it lacks significant anti-tumor activity on its own,[A274688] it has been extensively investigated for nearly a decade as a biochemical modulator to enhance the efficacy and reduce the … toxicity of established anti-metabolite chemotherapeutic agents, such as 5-Fluorouracil (FU), Methotrexate (MTX), and Cytosine arabinoside (ara-C).
Categories: Heterocyclic Compounds, 1-RingSynonyms: MT-1621 COMPONENT 2'-DEOXYTHYMIDINE, 1-(2-Deoxy-?-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol))
go.drugbank.com/drugs/DB11331ApprovedWithdrawnPalmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as a surfactant [FDA Label].
Synonyms: PG(16:0/18:1), PG(16:0/18:1(9Z))Salts: 1-palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt1-Naphthylamine-5-sulfonic acid
go.drugbank.com/drugs/DB07176ExperimentalSynonyms: 1-Amino-5-sulfonaphthalene, 1-Amino-5-naphthalenesufonic acid1-Deoxy-Ribofuranose-5'-Phosphate
go.drugbank.com/drugs/DB03936ExperimentalSynonyms: 1-Deoxy-Ribofuranose-5'-PhosphateFinasteride
go.drugbank.com/drugs/DB01216ApprovedInvestigationalIt works in a similar fashion as [dutasteride], which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. … [L6244] Finasteride is commonly marketed under the brand names Propecia and Proscar to be used aloneo or in combination with [doxazosin], an alpha-blocker.
Mixtures: Finasteride 0.1% / Minoxidil 5%, Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5%Categories: 5-alpha Reductase Inhibitors, Cytochrome P-450 SubstratesFlucytosine
go.drugbank.com/drugs/DB01099ApprovedInvestigationalA fluorinated cytosine analog that is used as an antifungal agent.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-FC, 5-FluorocytosineCholesteryl Linoleate
go.drugbank.com/drugs/DB02092ExperimentalSynonyms: (3β)-cholest-5-en-3-ol, (Z,Z)-9,12-octadecadienoate, cholest-5-en-3β-yl (Z,Z)-octadeca-9,12-dienoateZavegepant
go.drugbank.com/drugs/DB15688ApprovedInvestigationalof oral zavegepant (150 mg bid) in subjects with mild allergic asthma. … Zavegepant is a third-generation CGRP receptor antagonist that is small in size and highly soluble. Due to its pharmacological properties, it can be administered intranasally.
Categories: MATE 1 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 1-piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-n-((1r)-1-((7-methyl-1h-indazol-5-yl)methyl)-2-(4-(1-methyl-4-piperidinyl)-1-piperazinyl)-2-oxoethyl)-Idelalisib
go.drugbank.com/drugs/DB09054ApprovedInvestigationalFor the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab alone would be considered appropriate therapy due to other … In contrast to the other class IA PI3Ks p110α and p110β, p110δ is principally expressed in leukocytes (white blood cells) and is important for the function of T cells, B cell, mast cells and neutrophils
Synonyms: 5-Fluoro-3-phenyl-2-((S)-1-(9H-purin-6-ylamino)-propyl)-3H-quinazolin-4-one, 5-fluoro-3-phenyl-2-[(1S)-1-(3H-purin-6-ylamino)propyl]quinazolin-4(3H)-oneCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexMethyltestosterone
go.drugbank.com/drugs/DB06710ApprovedInvestigationalA synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. … Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.
Categories: 3-Oxoandrosten (4) Derivatives, Cytochrome P-450 SubstratesSynonyms: 17-beta-Hydroxy-17-methylandrost-4-en-3-one, 17beta-Hydroxy-17-methylandrost-4-en-3-one