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Cyclophosphamide
go.drugbank.com/drugs/DB00531ApprovedInvestigationalIt has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester, 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxideTacrolimus
go.drugbank.com/drugs/DB00864ApprovedInvestigationalIt was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. … Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection.
Mixtures: Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20%Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsRocuronium
go.drugbank.com/drugs/DB00728ApprovedInvestigational[Sugammadex] is a γ-cyclodextrin derivative that has been introduced as a novel agent to reverse the action of rocuronium. … The drug is associated with the risk of developing allergic reactions in some high-risk patients, such as those with asthma.
Products: ANTARİN 100 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 10 ADET, JECRON 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ ,10 FLAKONLevothyroxine
go.drugbank.com/drugs/DB00451ApprovedInvestigationalStimulating Hormone (TSH) release by the pituitary gland, a normally functioning thyroid gland will produce and secrete T<sub>4</sub>, which is then converted through deiodination (by type I or type II 5′ … [A179935] As a result, many cardiac functions including heart rate, cardiac output, and systemic vascular resistance are closely linked to thyroid status.
Mixtures: BITIRON 50 MCG/12.5 MCG TABLET, 100 ADET, SYNTHROID® 112 MCG TABLETASCategories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 Enzyme InhibitorsAmoxicillin
go.drugbank.com/drugs/DB01060ApprovedInvestigationalVet approvedAmoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. … [A190648] Amoxicillin was granted FDA approval on 18 January 1974.[L11644]
Mixtures: AMOXICLAV BASI 500MG/125MG, AMOXICLAV BASI 500MG/125MGCategories: Penicillin G, Cytochrome P-450 CYP2C8 InhibitorsIopamidol
go.drugbank.com/drugs/DB08947ApprovedInvestigationalIopamidol is a contrast agent developed by Bracco with nonionic, low-osmolar properties.
Products: PAMIRAY 370 ENJ. 50 ML 0,755 MG FLAKON, 1 ADET, PAMİRAY 300 MG/ML IV/İNTRAARTİKÜLER/İNTRATEKAL ENJEKSİYONLUK ÇÖZELTİ (50 ML)Ibuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigational[A39075] Ibuprofen was finally patented in 1961 and this drug was first launched against rheumatoid arthritis in the UK in 1969 and USA in 1974. It was the first available over-the-counter NSAID. … [A39076] On the available products, ibuprofen is administered as a racemic mixture.
Mixtures: ML-PRIM, COLDFEN 100 MG+15 MG+1 MG/5 ML ŞURUP, 100 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesValproic acid
go.drugbank.com/drugs/DB00313ApprovedInvestigational[L6190] Since then, it has been investigated for neuroprotective, anti-manic, and anti-migraine effects. … [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century.
Mixtures: PROKSIVAL XR 500 MG UZUN ETKILI FILM TABLET, 50 ADET, PROKSIVAL XR 500 MG UZUN ETKILI FILM TABLET, 50 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsMevonlerbart
go.drugbank.com/drugs/DB19416InvestigationalMevonlerbart is under investigation in clinical trial NCT06602726 (A Study to Demonstrate How Well REGN1908-1909 Works in Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Cat Allergy).
Synonyms: gamma4 heavy chain Homo sapiens (1-442) [VH (Homo sapiens IGHV3-23*04 (94.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.8] (26-33.51-58.97-104)) (1-115)-Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH2 L92Naproxen
go.drugbank.com/drugs/DB00788ApprovedInvestigationalVet approved[A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. … Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994.
Mixtures: TIYOKSEN 550 MG/8 MG FILM TABLET,10 ADET, APRANAX PLUS 550 MG/30 MG FILM KAPLI TABLET, 10 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates