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Displaying results 1871 - 1880 of 7895 in total
  1. Drug

    p-tert-Butylphenol-formaldehyde resin (low molecular weight)

    go.drugbank.com/drugs/DB14190
    Approved

    p-tert-Butylphenol-formaldehyde resin is a widely used adhesive chemical used in a wide variety of commercially available products and a known dermatological sensitizer and allergen [A34290,A34291]. … Sensitivity to p-tert-Butylphenol-formaldehyde resin may be identified with a clinical patch test.

  2. Drug

    Invert sugar

    go.drugbank.com/drugs/DB09344
    Experimental

    [A32124] Invert sugar is FDA approved since 1988 as a safe substance (GRAS). … It is formed by an equal amount of glucose and fructose. It differentiates from sugar cane in the rotation of the polarized light, which in the case of invert sugar it is to the left (levorotatory).

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Modafinil

    go.drugbank.com/drugs/DB00745
    ApprovedInvestigational

    Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. … Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil.

  4. Drug

    Olsalazine

    go.drugbank.com/drugs/DB01250
    Approved

    Olsalazine is an aminosalicylate and a prodrug of [mesalamine] (5-aminosalicylic acid, 5-ASA). … [A257078] Olsalazine comprises two mesalamine molecules joined by an azo bridge, which is cleaved in the colon.

  5. Drug

    Bos taurus dander

    go.drugbank.com/drugs/DB11020
    Approved

    Bos taurus dander allergenic extract is used in allergenic testing.

    Mixtures: Animal Allergens, AP Cattle Hair and Dander, Animal Allergens, AP Cattle Hair and Dander
  6. Drug

    Fidanacogene elaparvovec

    go.drugbank.com/drugs/DB16783
    ApprovedInvestigational

    Fidanacogene elaparvovec is a liver-specific adeno-associated virus (AAV) vector containing a codon-optimized human coagulation FIX gene that was investigated as a potential treatment for hemophilia B. … from week 12 to month 15 compared to an ABR of 4.43 for the pre-treatment period.

  7. Drug

    Palovarotene

    go.drugbank.com/drugs/DB05467
    Approved

    It first garnered interest as a potential treatment for emphysema but was eventually recognized as a potential novel therapy for patients with FOP. … ], which are derivatives of [vitamin A].

  8. Drug

    Tisotumab vedotin

    go.drugbank.com/drugs/DB16732
    ApprovedInvestigational

    Tisotumab vedotin is a tissue factor-directed antibody-drug conjugate (ADC) comprised of an anti-tissue factor (TF) human IgG1-kappa antibody conjugated to monomethyl auristatin E (MMAE), a microtubule-disrupting … agent, via a protease-cleavable valine-citrulline linker.

  9. Drug

    Pramiracetam

    go.drugbank.com/drugs/DB13247
    Approved

    Pramiracetam has been studied for the use in Alzheimer's disease and as an adjunct treatment to restore cognitive functioning post-electroconvulsive therapy in severe depression [L5470].

  10. Drug

    Imlunestrant

    go.drugbank.com/drugs/DB19043
    ApprovedInvestigational

    progression on at least one line of endocrine therapy. … Imlunestrant is a brain-penetrant selective estrogen receptor antagonist and degrader.