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Displaying results 181 - 190 of 10818 in total
  1. Drug

    Ergidina

    go.drugbank.com/drugs/DB18565
    Experimental

    Ergidina is a recombinant human minibody against complement component C5 fused with RGD-motif.

    Synonyms: Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 and the cyclic RGD-4C peptide (ACDCRGDCFCG)
  2. Drug

    Ociperlimab

    go.drugbank.com/drugs/DB18947
    Investigational

    Ociperlimab is under investigation in clinical trial NCT04866017 (A Study to Compare Ociperlimab Plus Tislelizumab Versus Durvalumab Following Concurrent Chemoradiotherapy (Ccrt) in Patients With Stage

    Synonyms: Immunoglobulin g1-kappa, anti-(homo sapiens tigit (t-cell immunoreceptor with ig domain and itim, v-set ig member 9, vsig9, v-set and transmembrane member 3, vstm3)), humanized monoclonal antibody (ociperlimab
  3. Drug

    Zifibancimig

    go.drugbank.com/drugs/DB19332
    Investigational

    Zifibancimig is under investigation in clinical trial NCT04567303, focusing on participants with neovascular age-related macular degeneration.

    Synonyms: Immunoglobulin G1 Fab fragment, bispecific, anti-(human vascular endothelial growth factor A and angiopoietin 2) (human monoclonal RO7250284 γ1-chain), disulfide with human monoclonal RO7250284 κ-chain, mmunoglobulin Fab G1-kappa, anti-[Homo sapiens ANGPT2 (angiopoietin 2, Ang2)] and anti-[Homo sapiens VEGFA (vascular endothelial growth factor A, VEGF-A, VEGF), monoclonal antibody, bispecific, biparatope
  4. Drug

    Azercabtagene zapreleucel

    go.drugbank.com/drugs/DB17185
    Investigational

    Synonyms: Adult allogeneic CD4+ and CD8+ enriched T cells transduced with an anti-CD19 chimeric antigen receptor (CAR) that is site-specific integrated into the cellular genome., Adult allogeneic CD4+ and CD8+ enriched T cells, gene edited through the electroporati
  5. Drug

    Tavokinogene telseplasmid

    go.drugbank.com/drugs/DB17301
    Investigational

    Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.

    Synonyms: Dna plasmid containing genes coding for the human interleukin 12 (il-12) p35 and p40 subunits that are separated by an internal ribosomal entry site (ires) and under the control of a single cytomegalovirus
  6. Drug

    NGN-401

    go.drugbank.com/drugs/DB18594
    Investigational

    NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding

    Synonyms: Recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2
  7. Drug

    NKX101

    go.drugbank.com/drugs/DB18131
    Investigational

    NKX101 is an investigational allogeneic chimeric antigen receptor (CAR)-natural killer cell therapy.

    Synonyms: a fourth generation activating chimeric receptor (ACR) natural killer (NK) cell therapy engineered with an NKG2D ACR, OX40 costimulatory domain, CD3zeta signaling moiety, and membrane bound IL-15 (mb-IL15
  8. Drug

    AD-214

    go.drugbank.com/drugs/DB18412
    Investigational

    Synonyms: Fc-fusion protein comprised of an anti-CXCR4 i-body tethered at its C-terminus to constant domains 2 and 3 of the Fc region of a mutated human IgG1
  9. Drug

    Lawsonia inermis leaf

    go.drugbank.com/drugs/DB14313
    Investigational

    It is not an approved drug.

    Synonyms: Plants and Plant Parts, Henna Lawsonia Inermis
  10. Drug

    AOC-1020

    go.drugbank.com/drugs/DB18621
    Investigational

    AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded

    Synonyms: An antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotide