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Displaying results 1901 - 1910 of 1914 in total
  1. Drug

    Divesiran

    go.drugbank.com/drugs/DB18646
    Investigational

    Divesiran is a synthetic double-stranded siRNA oligonucleotide directed against TMPRSS6 mRNA and covalently linked to a ligand containing 3 N-acetylgalactosamine residues.

  2. Drug

    Palopegteriparatide

    go.drugbank.com/drugs/DB18676
    ApprovedInvestigational

    [L51134] PTH(1-34) contains the N-terminal part of the endogenous PTH molecule.

    Synonyms: Human parathyroid hormone (PTH) synthetic peptide fragment (1-34), conjugated at the N-terminal amino group via a cleavable linker to O-methylpolyethylene glycol (2 x 20 kDa mPEG); 2-methylalanyl-(1-34, Poly(oxy-1,2-ethanediyl), α-hydro-ω-methoxy-, ether with N-[[[2-[[6-[[1-[3-[[3-(2,3-dihydroxypropoxy)propyl]amino]-3-oxopropyl]-2,5-dioxo-3-pyrrolidinyl]thio]hexyl]amino]ethyl]amino]carbonyl]-2-methylalanyl-L-seryl-L-valyl-L-seryl-L-α-glutamyl-L-isole
  3. Drug

    Olezarsen

    go.drugbank.com/drugs/DB18728
    ApprovedInvestigational

    [A264888,A264893] Olezarsen is conjugated to a ligand containing three N-acetyl-galactosamine (GalNAc) residues to enable its delivery to hepatocytes.

  4. Drug

    Plozasiran

    go.drugbank.com/drugs/DB18997
    ApprovedInvestigational

    Plozasiran contains a covalently linked ligand containing three N-acetylgalactosamine (GalNAc) residues to facilitate delivery to hepatocytes where it works to reduce triglyceride levels.

  5. Drug

    Nelistotug

    go.drugbank.com/drugs/DB19334
    Investigational

    NCT06062420 (A Platform Study of Novel Immunotherapy Combinations as First-line Treatment in Participants With PD-L1 Positive Recurrent/metastatic Squamous Cell Carcinoma of the Head and Neck- GALAXIES H&N-

  6. Drug

    Nestifylline

    go.drugbank.com/drugs/DB19989
    Experimental

    The usage of the INN stem '-fylline' in the name indicates that Nestifylline is a N-methylated xanthine derivative. Nestifylline has a monoisotopic molecular weight of 298.06 Da.

  7. Drug

    Torbafylline

    go.drugbank.com/drugs/DB20095
    Experimental

    The usage of the INN stem '-fylline' in the name indicates that Torbafylline is a N-methylated xanthine derivative. Torbafylline has a monoisotopic molecular weight of 338.2 Da.

  8. Drug

    Perbufylline

    go.drugbank.com/drugs/DB20935
    Experimental

    The usage of the INN stem '-fylline' in the name indicates that Perbufylline is a N-methylated xanthine derivative. Perbufylline has a monoisotopic molecular weight of 441.22 Da.

  9. Drug

    Flufylline

    go.drugbank.com/drugs/DB21020
    Experimental

    The usage of the INN stem '-fylline' in the name indicates that Flufylline is a N-methylated xanthine derivative. Flufylline has a monoisotopic molecular weight of 413.19 Da.

  10. Drug

    Acefylline clofibrol

    go.drugbank.com/drugs/DB21353
    Experimental

    The usage of the INN stem '-fylline' in the name indicates that Acefylline clofibrol is a N-methylated xanthine derivative. Acefylline clofibrol has a monoisotopic molecular weight of 420.12 Da.