Search

Displaying results 191 - 200 of 145270 in total
  1. Drug

    Afamitresgene autoleucel

    go.drugbank.com/drugs/DB18592
    ApprovedInvestigational

    [L51114] The transduced T cells are expanded, washed, formulated into a suspension, and cryopreserved. … [L51114] MAGE-A4 is an intracellular cancer-testis antigen that is overexpressed by cancer cells in synovial sarcoma.

    Synonyms: AUTOLOGOUS CD4+ AND CD8+ T CELLS OBTAINED BY LEUKAPHERESIS, TRANSDUCED WITH AN HIV-DERIVED SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING AN ENHANCED-AFFINITY T CELL RECEPTOR (TCR) SPECIFIC FOR THE
  2. Drug

    Pomegranate

    go.drugbank.com/drugs/DB14317
    Investigational

    It is not an approved drug.

    Synonyms: Dadima Fruit, Shi Liu Fruit
  3. Drug

    Medical Cannabis

    go.drugbank.com/drugs/DB14009
    Investigational

    to contain different concentrations of CBD and THC. … Due to the differences in receptor profile between CBD and THC, these cannabinoids are understandably used to treat different conditions.

    Synonyms: Hashish top, Marijuana top
  4. Drug

    Atidarsagene autotemcel

    go.drugbank.com/drugs/DB17538
    ApprovedInvestigational

    Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced _ex vivo_ using … [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic

    Synonyms: Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) geneCategories: Enzymes and Coenzymes, Alimentary Tract and Metabolism
  5. Drug

    Radotermin

    go.drugbank.com/drugs/DB19127
    Investigational

    Radotermin is under investigation in clinical trial NCT01182337 (A Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal Rhgdf-5 for the

    Synonyms: Recombinant human growth and differentiation factor-5
  6. Drug

    Romilkimab

    go.drugbank.com/drugs/DB16318
    Investigational

    Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).

    Synonyms: Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13)
  7. Drug

    Vitex agnus-castus fruit extract

    go.drugbank.com/drugs/DB13193
    Investigational

    The main mechanism of action of vitex agnus-castus fruit extract has not been fully elucidated, however it is suggested to modulate the stress-induced prolactin secretion via dopaminergic actions, and … The fruits contain mixture of iridoids, flavonoids and compounds in leaves and flowers that structurally resemble sex hormones.

    Synonyms: Vitex agnus-castus fruit extractCategories: Genito Urinary System and Sex Hormones
  8. Drug

    Mucor circinelloides f. circinelloides

    go.drugbank.com/drugs/DB15512
    Approved

    Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.

    Synonyms: Molds, rusts and smuts, mucor circinelloides f. circinelloides
  9. Drug

    Althea root

    go.drugbank.com/drugs/DB13525
    Experimental

    Synonyms: Althaea officinalis rootCategories: Cough and Cold Preparations
  10. Drug

    Nogapendekin alfa

    go.drugbank.com/drugs/DB18740
    ApprovedInvestigational

    [A263617, A263622] Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which … Nogapendekin alfa is a human IL-15N72D variant.

    Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsSynonyms: Fusion protein consisting of il-15n72d and il-15rasu/fc, IL-15N72D