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PEP0101
go.drugbank.com/drugs/DB18572ExperimentalPEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Synonyms: Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and an elastin-like polypeptide drug carrier.Acapatamab
go.drugbank.com/drugs/DB18838InvestigationalAcapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Synonyms: Mmunoglobulin scfv-scfv-scfc, anti-(homo sapiens folh1 (folate hydrolase, prostate specific membrane antigen, psma)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chainCibisatamab
go.drugbank.com/drugs/DB17349InvestigationalSynonyms: Humanized immunoglobulin g1 (igg1) t-cell bispecific (tcb) antibody targeting carcinoembryonic antigen (cea) and cd3 epsilon chain (cd3e) on t-cellsCategories: Amino Acids, Peptides, and ProteinsTVI-Brain-1
go.drugbank.com/drugs/DB17227InvestigationalSynonyms: Attenuated autologous cancer cells and granulocyte macrophage colony stimulating factor in combination with activated autologous blood derived T-cellsDelolimogene mupadenorepvec
go.drugbank.com/drugs/DB17326InvestigationalSynonyms: Dna (synthetic human adenovirus 5/35 vector load703 human cd137 ligand and trimerized membrane-bound isoleucine zipper-containing human cd40 ligand-specifying)Hiltonol
go.drugbank.com/drugs/DB17293InvestigationalSynonyms: 5'-cytidylic acid, homopolymer, complex with 5'-inosinic acid homopolymer (1:1), compd. with cellulose carboxymethyl ether and l-lysine homopolymer, L-lysine, homopolymer, compd. with cellulose carboxymethyl ether and 5'-inosinic acid homopolymer complex with 5'-cytidylic acid homopolymerCategories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsParasorbic acid
go.drugbank.com/drugs/DB14121InvestigationalSole constituent of "Vogelbeerol" oil obtained by steam distillation of the acidified juice of the ripe berries of the mountain ash.
Synonyms: Sorbic oil, 2-Hexen-5,1-olideCotsiranib
go.drugbank.com/drugs/DB18404InvestigationalSynonyms: STP705 (small interfering RNA (siRNA) therapeutic directed against transforming growth factor-beta 1 (TGF-beta 1) and cyclo-oxygenase-2 (COX-2))Suratadenoturev
go.drugbank.com/drugs/DB18672InvestigationalSuratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Synonyms: A recombinant replication-competent adenovirus type 5 (Ad-5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and replaced by an expression cassette containing, A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human telomerase reverse transcriptase (hTERT) and IRES, respectively.