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Spebrutinib
go.drugbank.com/drugs/DB11764InvestigationalSpebrutinib has been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and Leukemia Lymphocytic Chronic B-Cell.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-(5-FLUORO-2-(4-(2-METHOXYETHOXY)PHENYLAMINO)PYRIMIDIN-4-YLAMINO)PHENYL)ACRYLAMIDE, N-(3-(5-fluoro-2-(4-(2-methoxyethoxy)phenylamino)pyrimidin-4-ylamino)phenyl)acrylamideTalinolol
go.drugbank.com/drugs/DB11770InvestigationalTalinolol has been investigated for the basic science of Gastrointestinal Motility Disorder.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesTremelimumab
go.drugbank.com/drugs/DB11771ApprovedInvestigationalCTLA-4 is a cell surface receptor expressed on activated T cells to act as a negative regulator for T cells. … Tremelimumab, formerly known as ticilimumab, is a fully human IgG2 monoclonal antibody directed against cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4).
Categories: CTLA-4-directed Blocking AntibodyProducts: IMJUDO®, IMJUDO® CONCENTRADO PARA SOLUCIÓN PARA INFUSIÓNPilaralisib
go.drugbank.com/drugs/DB11772InvestigationalPilaralisib is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 kinase (PI3K).
Categories: Heterocyclic Compounds, 2-Ring, Phosphatidylinositol 3-Kinases, antagonists & inhibitorsPazufloxacin
go.drugbank.com/drugs/DB11774InvestigationalPazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol).
Categories: 4-Quinolones, Heterocyclic Compounds, 1-RingDanoprevir
go.drugbank.com/drugs/DB11779InvestigationalDanoprevir has been used in trials studying the treatment of Hepatitis C, Chronic.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP3A InhibitorsAllicin
go.drugbank.com/drugs/DB11780InvestigationalAllicin has been used in trials studying the treatment of Follicular Lymphoma.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsBirinapant
go.drugbank.com/drugs/DB11782InvestigationalBirinapant has been investigated for the treatment of Myelodysplastic Syndrome (MDS) and Chronic Myelomonocytic Leukemia (CMML).
Categories: Heterocyclic Compounds, 2-RingNeuropeptide Y
go.drugbank.com/drugs/DB11788ApprovedInvestigationalWithdrawnNeuropeptide Y is under investigation for the basic science of Type 2 Diabetes Mellitus.
Categories: Neuropeptide Y, drug effectsSynonyms: Neuropeptide YFostemsavir
go.drugbank.com/drugs/DB11796ApprovedInvestigationalFostemsavir is the phosphonooxymethyl prodrug of temsavir, a novel HIV-1 attachment inhibitor. … HIV-1 fills a necessary niche for therapeutic options in patients left with few, if any, viable treatments.
Categories: Human Immunodeficiency Virus Type 1 (HIV-1) gp120-directed Attachment Inhibitors, Cytochrome P-450 Substrates