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Displaying results 2111 - 2120 of 10000 in total
  1. Drug

    PEP0101

    go.drugbank.com/drugs/DB18572
    Experimental

    PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.

    Synonyms: Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and an elastin-like polypeptide drug carrier.
  2. Drug

    Iberdomide

    go.drugbank.com/drugs/DB12101
    Investigational

    at least one prior line of therapy including a proteasome inhibitor and an immunomodulatory agent. … [L64055] Iberdomide has shown anti-tumor activity in multiple myeloma cells resistant to lenalidomide and pomalidomide, and as a CELMoD is designed to degrade Ikaros and Aiolos more potently than immunomodulatory

    Categories: Cereblon E3 ligase modulator, Cytochrome P-450 SubstratesSynonyms: (S)-3-(4-((4-(Morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, 2,6-Piperidinedione, 3-(1,3-dihydro-4-((4-(4-morpholinylmethyl)phenyl)methoxy)-1-oxo-2H-isoindol-2-yl)-, (3S)-
  3. Drug

    MB07133

    go.drugbank.com/drugs/DB17139
    Investigational

    Synonyms: (2R,4S)-4-amino-1-(5-O-(2-oxo-4-(4-pyridyl)-1,3,2-dioxaphosphorinan-2-yl)-beta-d-arabinofuranosyl)-2(1H)-pyrimidinone, 4-Amino-1-[5-O-[(2R, 4S)-2-oxido-4-(4-pyridinyl)-1, 3, 2-dioxaphosphorinan-2-yl]-b-D-arabinofuranosyl]-2(1H)-pyrimidinoneCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Amoscanate

    go.drugbank.com/drugs/DB21356
    Experimental

    Amoscanate is a small molecule drug. Amoscanate has a monoisotopic molecular weight of 271.04 Da.

    Synonyms: 4-isothiocyanato-4'-nitrodiphenylamine, P-(p-nitroanilino)phenyl isothiocyanate
  5. Drug

    Berberine ursodeoxycholate

    go.drugbank.com/drugs/DB18111
    Investigational

    Synonyms: 9,10-dimethoxy-5,6-dihydro-2H,8H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-8-ylium 3α,7β-dihydroxy-5β-cholan-24-oate, Cholan-24-oic acid, 3,7-dihydroxy-, ion(1-), (3α,5β,7β)-, 5,6-dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium (1:1)
  6. Drug

    Pipequaline

    go.drugbank.com/drugs/DB13991
    Experimental

    However, it presents a significant set of anxiolytic properties with a very little sedative, amnestic or anticonvulsant effect. … Pipequaline is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-Phenyl-4-(2-(4-piperidyl)ethyl)quinoline
  7. Drug

    GTB-3550

    go.drugbank.com/drugs/DB18494
    Investigational

    GTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form

    Synonyms: single chain recombinant trispecific killer engager consistent of anti-CD16 scFV spliced to anti-CD33 scFV with a modified IL-15 linker
  8. Drug

    Rosaramicin

    go.drugbank.com/drugs/DB20624
    Experimental

    Rosaramicin is a small molecule drug. Rosaramicin has a monoisotopic molecular weight of 581.36 Da.

    Synonyms: 4'-deoxycirramycin a1, Cirramycin a1, 4'-deoxy-
  9. Drug

    LB54640

    go.drugbank.com/drugs/DB18331
    Investigational

    LB54640 is orally-administered small molecule agonist of the melanocortin 4 receptor.

    Synonyms: Oral melanocortin 4 receptor agonist, Small molecule melanocortin 4 receptor agonist
  10. Drug

    Ozanezumab

    go.drugbank.com/drugs/DB12891
    Investigational

    Ozanezumab has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis, Relapsing-Remitting.

    Synonyms: IMMUNOGLOBULIN G1, ANTI-(PROTEIN NOGO-A) (HUMAN-MUS MUSCULUS MONOCLONAL HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL LIGHT CHAIN, DIMER