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Levothyroxine
go.drugbank.com/drugs/DB00451ApprovedInvestigationalquantities of the thyroid hormones T<sub>4</sub> (tetraiodothyronine or thyroxine) and T<sub>3</sub> (triiodothyronine or [DB00279]), resulting in diminished down-stream effects of these hormones. … potency of ~1:4 (T4:T3).
Synonyms: O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine, O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosineProducts: EUTHYROX 50 UG, EUTHYROX 100 UGAzacitidine
go.drugbank.com/drugs/DB00928ApprovedInvestigationalmyeloid leukemia (AML), two types of cancer characterized by the presence of aberrant DNA methylation. … One of them is the induction of cytotoxicity. As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and inhibiting protein and DNA synthesis.
Products: Azacitidin EVER Pharma 25 mg/ml Pulver zur Herstellung einer Injektionssuspension, AZACITIDINA EGMitotane
go.drugbank.com/drugs/DB00648ApprovedInvestigationaltheir production of hormones. … Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and
Synonyms: o,p'-DDDProducts: LYSODREN ® 500 MG COMPRIMIDOSDiacerein
go.drugbank.com/drugs/DB11994ApprovedInvestigationalWithdrawnIt is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including severe diarrhea [L780]. … Diacerein is under investigation for the treatment of Insulin Resistance, Diabetes Mellitus (Type 2), and Diabetes-Related Complications.
Products: Artrolyt 50 mg Kapseln, DIACEREINA 50 MG.Lovastatin
go.drugbank.com/drugs/DB00227ApprovedInvestigational[A181087,A181553] Use of statins to target and reduce LDL levels has been shown in a number of landmark studies to significantly reduce the risk of development of CVD and all-cause mortality. … The clear evidence of the benefit of statin use coupled with very minimal side effects or long term effects has resulted in this class becoming one of the most widely prescribed medications in North America
Products: Nu-lovastatin Tablets, LOSTIN® 20 MGCarisoprodol
go.drugbank.com/drugs/DB00395Approvedfor abuse in addition to a low risk of dependence [L5074]. … This drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with both aspirin and codeine [FDA label, F4060, F4069].
Products: Carisoprodol Tablets, USP, 350 mgRosin
go.drugbank.com/drugs/DB11165ApprovedRosin has shown to mediate antibacterial actions on Gram-positive bacterial species [A27267]. … Rosin is a solid form of resin obtained from pines and other plants, mostly conifers. It is prepared from heating fresh liquid resin to vaporize the volatile liquid terpene components.
Categories: Compounds used in a research, industrial, or household settingDordaviprone
go.drugbank.com/drugs/DB14844ApprovedInvestigational[A274391] Dordaviprone has several modes of action, including the activation of mitochondrial caseinolytic protease P (ClpP), antagonism of the dopamine D2 receptor,[L53833] activation of Activating Transcription … Factor 4 (ATF4), and induction of endoplasmic reticulum (ER) stress response.
Propolis wax
go.drugbank.com/drugs/DB11355ApprovedInvestigationalPropolis wax is naturally produced by honeybees by mixing the resin or exudate collected from tree buds, sap flows, or other botanical sources with beeswax that contains fatty acids and bee enzymes.
Mixtures: Dr.bro MAN OF SENSE Mans CleanserPotassium bitartrate
go.drugbank.com/drugs/DB11107ApprovedInvestigationalPotassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium acid salt of l-( + )-tartaric acid. … Potassium bitartrate was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.[L14120]