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Displaying results 2181 - 2190 of 10000 in total
  1. Drug

    Grazoprevir

    go.drugbank.com/drugs/DB11575
    Approved

    Subtitutions at amino acid positions 155, 156, or 168 are known to confer resistance. … When combined together, Grazoprevir and [DB11574] as the combination product Zepatier have been shown to achieve a SVR between 94% and 97% for genotype 1 and 97% and 100% for genotype 4 after 12 weeks

    Mixtures: ZEPATIER 50 MG/100 MG FİLM KAPLI TABLET, 28 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  2. Drug

    Fenobam

    go.drugbank.com/drugs/DB12931
    Investigational

    Fenobam is under investigation in clinical trial NCT00637221 (Open Label Study Investigating Safety and Efficacy of Fenobam anhydrous 50 mg - 150 mg on Prepulse Inhibition Tests and Continuous Performance

  3. Drug

    Maritime pine extract

    go.drugbank.com/drugs/DB15786
    Investigational

    Categories: Compounds used in a research, industrial, or household settingProducts: LACORYL ® 60 MG CAPSULAS
  4. Drug

    Pinazepam

    go.drugbank.com/drugs/DB13335
    Investigational

    Products: DOMAR CAPSULE 5 mg
  5. Drug

    Bictegravir

    go.drugbank.com/drugs/DB11799
    ApprovedInvestigational

    It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.[L43677] … Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection.

    Mixtures: BİKTARVY 50 MG / 200 MG / 25 MG FİLM KAPLI TABLET, 30 TABLET, BİKTARVY 50 MG / 200 MG / 25 MG FİLM KAPLI TABLET, 90 TABLETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  6. Drug

    Ketobemidone

    go.drugbank.com/drugs/DB06738
    Investigational

    The most commonly cited equalisation ratio for analgesic doses is 25 mg of ketobemidone hydrobromide to 60 mg of morphine hydrochloride or sulfate and circa 8 mg of ketobemidone by injection. … Ketobemidone is a powerful opioid analgesic. It also has some NMDA-antagonist properties. This makes it useful for some types of pain that don't respond well to other opioids.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  7. Drug

    Dihydro-alpha-ergocryptine

    go.drugbank.com/drugs/DB11274
    Approved

    These two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine. … Alpha-dihydroergocryptine approved drug product is as a part of an ergoloid mixture. To know more about this mixture, please visit [DB01049]

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  8. Drug

    Carbamoylcholine

    go.drugbank.com/drugs/DB00411
    Approved

    Carbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932. … [A226315] Carbamoylcholine was initially used as a treatment for migraines,[A226365] induction of diuresis,[A226370] and other parasympathetic effects.

    Categories: Compounds used in a research, industrial, or household settingProducts: Carbachol Injection Liq Sc 0.25mg/ml, Carbachol Tab 2mg
  9. Drug

    Bibrocathol

    go.drugbank.com/drugs/DB13818
    Investigational

    Products: Bibrocathol-POS 20 mg/g Augensalbe
  10. Drug

    Pemafibrate

    go.drugbank.com/drugs/DB15212
    Investigational

    Pemafibrate is under investigation in clinical trial NCT03350165 (A Study of Pemafibrate in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)).

    Products: PARMODIA Film-coated Tablets 0.1 mg